N-tert-butoxycarbonyl-L-leucyl-O-benzyl-L-tyrosyl-L-leucyl-L-valine methyl ester

Base Information

Chemical Name:N-tert-butoxycarbonyl-L-leucyl-O-benzyl-L-tyrosyl-L-leucyl-L-valine methyl ester
CAS No.:82176-10-1
Molecular Formula:C₃₉H₅₈N₄O₈
Molecular Weight:710.912
Hs Code.:

Synonyms:N-tert-butoxycarbonyl-L-leucyl-O-benzyl-L-tyrosyl-L-leucyl-L-valine methyl ester

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-tert-butoxycarbonyl-L-leucyl-O-benzyl-L-tyrosyl-L-leucyl-L-valine methyl ester

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Technology Process of N-tert-butoxycarbonyl-L-leucyl-O-benzyl-L-tyrosyl-L-leucyl-L-valine methyl ester

There total 1 articles about N-tert-butoxycarbonyl-L-leucyl-O-benzyl-L-tyrosyl-L-leucyl-L-valine methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 3350-19-4
(tert-butoxycarbonyl)-L-leucine p-nitrobenzylester

: 82176-09-8
O-benzyl-L-tyrosyl-L-leucyl-L-valine methyl ester trifluoroacetate

: 82176-10-1
N-tert-butoxycarbonyl-L-leucyl-O-benzyl-L-tyrosyl-L-leucyl-L-valine methyl ester

Guidance literature:: With triethylamine; In N,N-dimethyl-formamide; at 4 ℃; for 48h;

Reference yield: 92.0%

: 82176-10-1
N-tert-butoxycarbonyl-L-leucyl-O-benzyl-L-tyrosyl-L-leucyl-L-valine methyl ester

: N-tert-butoxycarbonyl-L-leucyl-O-benzyl-L-tyrosyl-L-leucyl-L-valine hydrazide

Guidance literature:: With hydrazine hydrate; In N,N-dimethyl-formamide; at 20 ℃; for 48h;

Reference yield:

: 82176-10-1
N-tert-butoxycarbonyl-L-leucyl-O-benzyl-L-tyrosyl-L-leucyl-L-valine methyl ester

: 82176-12-3
N-tert-butoxycarbonyl-L-leucyl-O-benzyl-L-tyrosyl-L-leucyl-L-valy-S-(acetamidomethyl)-L-cysteinyl-glycine methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 92 percent / hydrazine hydrate / dimethylformamide / 48 h / 20 °C

2: 1.) HCl, butyl nitrite, 2.) triethylamine / 1.) dimethylformamide, tetrahydrofuran, -20 deg C, 45 min, 2.) 4 - 20 deg C, 54 h

With hydrogenchloride; n-Butyl nitrite; hydrazine hydrate; triethylamine; In N,N-dimethyl-formamide;