acetyl-1 hydroxy-4 butylidenetriphenylphosphorane

Base Information

• Chemical Name: acetyl-1 hydroxy-4 butylidenetriphenylphosphorane
• CAS No.: 80645-41-6
• Molecular Formula: C₂₄H₂₅O₂P
• Molecular Weight: 376.435
• Mol file: 80645-41-6.mol

Synonyms:acetyl-1 hydroxy-4 butylidenetriphenylphosphorane

Chemical Property of acetyl-1 hydroxy-4 butylidenetriphenylphosphorane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of acetyl-1 hydroxy-4 butylidenetriphenylphosphorane

There total 4 articles about acetyl-1 hydroxy-4 butylidenetriphenylphosphorane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

[4-(acetyloxy)butyl]triphenylphosphonium bromide (6191-70-4) → acetyl-1 hydroxy-4 butylidenetriphenylphosphorane (80645-41-6)

Guidance literature:

With potassium tert-butylate; In tert-butyl alcohol; for 8h; Heating;

DOI:10.1016/S0040-4020(01)92356-7

Reference yield:

4-bromobutylphosphonium bromide (7333-63-3) → acetyl-1 hydroxy-4 butylidenetriphenylphosphorane (80645-41-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 88 percent / acetone; H₂O / 15 h / Heating

2: 67 percent / t-BuOK / 2-methyl-propan-2-ol / 8 h / Heating

With potassium tert-butylate; In water; acetone; tert-butyl alcohol;

DOI:10.1016/S0040-4020(01)92356-7

Reference yield:

triphenylphosphine (603-35-0) → acetyl-1 hydroxy-4 butylidenetriphenylphosphorane (80645-41-6)

Guidance literature:

Multi-step reaction with 3 steps

1: 85 percent / toluene / 15 h / Heating

2: 88 percent / acetone; H₂O / 15 h / Heating

3: 67 percent / t-BuOK / 2-methyl-propan-2-ol / 8 h / Heating

With potassium tert-butylate; In water; acetone; toluene; tert-butyl alcohol;

DOI:10.1016/S0040-4020(01)92356-7

upstream raw materials:

[4-(acetyloxy)butyl]triphenylphosphonium bromide

4-bromobutylphosphonium bromide

triphenylphosphine