(2S,3S)-2-[3-(2-Dimethylaminomethyl-4-methoxy-phenyl)-3-trimethylsilanyl-propyl]-2-methyl-3-vinyl-cyclopentanone

Base Information

Chemical Name:(2S,3S)-2-[3-(2-Dimethylaminomethyl-4-methoxy-phenyl)-3-trimethylsilanyl-propyl]-2-methyl-3-vinyl-cyclopentanone
CAS No.:76463-50-8
Molecular Formula:C₂₄H₃₉NO₂Si
Molecular Weight:401.665
Hs Code.:

Synonyms:(2S,3S)-2-[3-(2-Dimethylaminomethyl-4-methoxy-phenyl)-3-trimethylsilanyl-propyl]-2-methyl-3-vinyl-cyclopentanone

Suppliers and Price of (2S,3S)-2-[3-(2-Dimethylaminomethyl-4-methoxy-phenyl)-3-trimethylsilanyl-propyl]-2-methyl-3-vinyl-cyclopentanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of (2S,3S)-2-[3-(2-Dimethylaminomethyl-4-methoxy-phenyl)-3-trimethylsilanyl-propyl]-2-methyl-3-vinyl-cyclopentanone

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2S,3S)-2-[3-(2-Dimethylaminomethyl-4-methoxy-phenyl)-3-trimethylsilanyl-propyl]-2-methyl-3-vinyl-cyclopentanone

There total 18 articles about (2S,3S)-2-[3-(2-Dimethylaminomethyl-4-methoxy-phenyl)-3-trimethylsilanyl-propyl]-2-methyl-3-vinyl-cyclopentanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 86284-19-7
{5-Methoxy-2-[1-trimethylsilanyl-3-((1S,2S)-1,8,8-trimethyl-2-vinyl-6,10-dioxa-spiro[4.5]dec-1-yl)-propyl]-benzyl}-dimethyl-amine

: 76463-50-8
(2S,3S)-2-[3-(2-Dimethylaminomethyl-4-methoxy-phenyl)-3-trimethylsilanyl-propyl]-2-methyl-3-vinyl-cyclopentanone

Guidance literature:: deketalization;
DOI:10.1021/ja00392a046

Reference yield:

: 83781-94-6
(2-chloro-5-methoxybenzyl)dimethylamine

: 76463-50-8
(2S,3S)-2-[3-(2-Dimethylaminomethyl-4-methoxy-phenyl)-3-trimethylsilanyl-propyl]-2-methyl-3-vinyl-cyclopentanone

Guidance literature:: Multi-step reaction with 4 steps

1: Ni

2: n-BuLi / tetrahydrofuran; hexamethylphosphoric acid triamide / 2 h / -20 - -10 °C

3: at -75 deg C to room temperature

4: 94 percent / deketalization

With n-butyllithium; nickel; In tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide;
DOI:10.1021/ja00392a046