C₂₄H₂₅N₃O₃

Base Information

• Chemical Name: C₂₄H₂₅N₃O₃
• CAS No.: 1309764-25-7
• Molecular Formula: C₂₄H₂₅N₃O₃
• Molecular Weight: 403.481
• Mol file: 1309764-25-7.mol

Synonyms:C₂₄H₂₅N₃O₃

Chemical Property of C₂₄H₂₅N₃O₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₄H₂₅N₃O₃

There total 4 articles about C₂₄H₂₅N₃O₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

9-amino-5-bromo-2-((1s,3s)-3-methylcyclobutyl)-2,3-dihydro-1H-pyrrolo[3,4-b]quinolin-1-one + 2,5-dimethoxyphenylboronic acid (107099-99-0) → C24H25N3O3 (1309764-25-7)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate; In 1,2-dimethoxyethane; ethanol; water; at 90 ℃;

DOI:10.1016/j.bmc.2011.03.035

Reference yield:

C16H16BrN3O (1309764-40-6) → C24H25N3O3 (1309764-25-7)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium t-butanolate / tert-butyl alcohol / 3 h / 45 °C

2: tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate / 1,2-dimethoxyethane; ethanol; water / 90 °C

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate; sodium t-butanolate; In 1,2-dimethoxyethane; ethanol; water; tert-butyl alcohol; 2: Suzuki coupling;

DOI:10.1016/j.bmc.2011.03.035

Reference yield:

C10H15NO2 (1309764-38-2) → C24H25N3O3 (1309764-25-7)

Guidance literature:

Multi-step reaction with 3 steps

1: methanesulfonic acid; acetic acid / 1.25 h / 80 °C

2: sodium t-butanolate / tert-butyl alcohol / 3 h / 45 °C

3: tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate / 1,2-dimethoxyethane; ethanol; water / 90 °C

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; methanesulfonic acid; potassium carbonate; acetic acid; sodium t-butanolate; In 1,2-dimethoxyethane; ethanol; water; tert-butyl alcohol; 3: Suzuki coupling;

DOI:10.1016/j.bmc.2011.03.035

upstream raw materials:

C₁₆H₁₆BrN₃O

2,5-dimethoxyphenylboronic acid

C₁₀H₁₅NO₂

3-Methyl-cyclobutylamin-⁽¹⁾