1-(4-Dimethylaminophenylimino-)-2-keto-2-(4-chlorphenyl-)-propionitril

Base Information

• Chemical Name: 1-(4-Dimethylaminophenylimino-)-2-keto-2-(4-chlorphenyl-)-propionitril
• CAS No.: 23071-71-8
• Molecular Formula: C₁₇H₁₄ClN₃O
• Molecular Weight: 311.771
• Mol file: 23071-71-8.mol

Synonyms:1-(4-Dimethylaminophenylimino-)-2-keto-2-(4-chlorphenyl-)-propionitril

Chemical Property of 1-(4-Dimethylaminophenylimino-)-2-keto-2-(4-chlorphenyl-)-propionitril

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(4-Dimethylaminophenylimino-)-2-keto-2-(4-chlorphenyl-)-propionitril

There total 5 articles about 1-(4-Dimethylaminophenylimino-)-2-keto-2-(4-chlorphenyl-)-propionitril which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-azido-4'-chloroacetophenone (26086-60-2) + potassium cyanide (151-50-8) + p-dimethylaminonitrosobenzene (138-89-6) → 1-(4-Dimethylaminophenylimino-)-2-keto-2-(4-chlorphenyl-)-propionitril (23071-71-8)

Guidance literature:

With piperdinium acetate; In methanol; at 30 ℃; for 1.33333h; Yield given;

Reference yield:

1-(2-(4-chlorophenyl)-2-oxoethyl)pyridinium bromide (26031-66-3) → 1-(4-Dimethylaminophenylimino-)-2-keto-2-(4-chlorphenyl-)-propionitril (23071-71-8)

Guidance literature:

Multi-step reaction with 2 steps

1: aqueous ethanol; aqueous NaOH-solution

2: aqueous ethanol

With sodium hydroxide; ethanol;

Reference yield:

1-(4-chloro-phenyl)-2-[(Z)-(4-dimethylamino-phenyl)-oxy-imino]-ethanone (52626-24-1) + sodium cyanide (143-33-9,25596-52-5) + p-dimethylaminonitrosobenzene (138-89-6) → 1-(4-Dimethylaminophenylimino-)-2-keto-2-(4-chlorphenyl-)-propionitril (23071-71-8)

Guidance literature:

With ethanol;

upstream raw materials:

1-(4-chloro-phenyl)-2-[(Z)-(4-dimethylamino-phenyl)-oxy-imino]-ethanone

sodium cyanide

p-dimethylaminonitrosobenzene

1-(2-(4-chlorophenyl)-2-oxoethyl)pyridinium bromide

Downstream raw materials:

4-chlorophenylglyoxylic acid

para-chlorobenzoic acid

3-(4-chloro-phenyl)-2,3-dioxo-propionic acid amide