Technology Process of C18H18BrNO3
There total 3 articles about C18H18BrNO3 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
C11H9BrO3;
With
C5H10O2*C24H23F12NOSi; trifluoroacetic acid;
In
ethyl acetate;
at -5 - 20 ℃;
Inert atmosphere;
1-(pyrrolidin-2-ylidene)propan-2-one;
With
sodium sulfate;
In
ethyl acetate;
Inert atmosphere;
DOI:10.1021/ol2017438
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: pyridine; dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 16 h / 0 - 20 °C / Inert atmosphere
2.1: pyridinium chlorochromate / dichloromethane / 16 h / 20 °C / Inert atmosphere
3.1: C5H10O2*C24H23F12NOSi; trifluoroacetic acid / ethyl acetate / -5 - 20 °C / Inert atmosphere
3.2: Inert atmosphere
With
pyridine; dmap; C5H10O2*C24H23F12NOSi; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; pyridinium chlorochromate; trifluoroacetic acid;
In
dichloromethane; ethyl acetate;
DOI:10.1021/ol2017438
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: pyridinium chlorochromate / dichloromethane / 16 h / 20 °C / Inert atmosphere
2.1: C5H10O2*C24H23F12NOSi; trifluoroacetic acid / ethyl acetate / -5 - 20 °C / Inert atmosphere
2.2: Inert atmosphere
With
C5H10O2*C24H23F12NOSi; pyridinium chlorochromate; trifluoroacetic acid;
In
dichloromethane; ethyl acetate;
DOI:10.1021/ol2017438
