N-(4-aminobutyl)-2-{1-(4-chlorobenzoyl)-5-methoxy-2′-trifluoromethyl-1H-indol-3-yl}acetamide hydrochloride

Base Information

Chemical Name:N-(4-aminobutyl)-2-{1-(4-chlorobenzoyl)-5-methoxy-2′-trifluoromethyl-1H-indol-3-yl}acetamide hydrochloride
CAS No.:1537876-08-6
Molecular Formula:C₂₃H₂₃ClF₃N₃O₃*ClH
Molecular Weight:518.363
Hs Code.:

Synonyms:N-(4-aminobutyl)-2-{1-(4-chlorobenzoyl)-5-methoxy-2′-trifluoromethyl-1H-indol-3-yl}acetamide hydrochloride

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Chemical Property of N-(4-aminobutyl)-2-{1-(4-chlorobenzoyl)-5-methoxy-2′-trifluoromethyl-1H-indol-3-yl}acetamide hydrochloride

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Technology Process of N-(4-aminobutyl)-2-{1-(4-chlorobenzoyl)-5-methoxy-2′-trifluoromethyl-1H-indol-3-yl}acetamide hydrochloride

There total 1 articles about N-(4-aminobutyl)-2-{1-(4-chlorobenzoyl)-5-methoxy-2′-trifluoromethyl-1H-indol-3-yl}acetamide hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 1537876-07-5
t-butyl N-4-[2-{1-(4-chlorobenzoyl)-5-methoxy-2′-trifluoromethyl-1H-indol-3-yl}acetamido]butyl carbamate

: 1537876-08-6
N-(4-aminobutyl)-2-{1-(4-chlorobenzoyl)-5-methoxy-2′-trifluoromethyl-1H-indol-3-yl}acetamide hydrochloride

Guidance literature:: With hydrogenchloride; In dichloromethane; at 25 ℃; for 1h;
DOI:10.1021/ml400485g

Reference yield: 63.0%

: 1537876-08-6
N-(4-aminobutyl)-2-{1-(4-chlorobenzoyl)-5-methoxy-2′-trifluoromethyl-1H-indol-3-yl}acetamide hydrochloride

: 209734-74-7
5-carboxy-X-rhodamine N-succinimidyl ester

: 1537876-09-7
N-{(5-carboxy-X-rhodaminyl)but-4-yl}-2-{1-(4-chlorobenzoyl)-5-methoxy-2′-trifluoromethyl-1H-indol-3-yl}-acetamide

Guidance literature:: N-(4-aminobutyl)-2-{1-(4-chlorobenzoyl)-5-methoxy-2′-trifluoromethyl-1H-indol-3-yl}acetamide hydrochloride; With triethylamine; In dimethyl sulfoxide; for 0.0833333h;

5-carboxy-X-rhodamine N-succinimidyl ester; In dimethyl sulfoxide; at 25 ℃; for 16h;
DOI:10.1021/ml400485g