N-(3,4-dichlorophenyl)-N'-(1-isopropyl-4-oxo-4,5-dihydro-1H-imidazol-2-yl)pyrrolidine-1-carboxamidine

Base Information

Chemical Name:N-(3,4-dichlorophenyl)-N'-(1-isopropyl-4-oxo-4,5-dihydro-1H-imidazol-2-yl)pyrrolidine-1-carboxamidine
CAS No.:1310682-63-3
Molecular Formula:C₁₇H₂₁Cl₂N₅O
Molecular Weight:382.293
Hs Code.:

Synonyms:N-(3,4-dichlorophenyl)-N'-(1-isopropyl-4-oxo-4,5-dihydro-1H-imidazol-2-yl)pyrrolidine-1-carboxamidine

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Chemical Property of N-(3,4-dichlorophenyl)-N'-(1-isopropyl-4-oxo-4,5-dihydro-1H-imidazol-2-yl)pyrrolidine-1-carboxamidine

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Technology Process of N-(3,4-dichlorophenyl)-N'-(1-isopropyl-4-oxo-4,5-dihydro-1H-imidazol-2-yl)pyrrolidine-1-carboxamidine

There total 7 articles about N-(3,4-dichlorophenyl)-N'-(1-isopropyl-4-oxo-4,5-dihydro-1H-imidazol-2-yl)pyrrolidine-1-carboxamidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

: 1310682-74-6
2-amino-1-isopropyl-1,5-dihydroimidazol-4-one

: 1310682-80-4
N-(3,4-dichlorophenyl)pyrrolidine-1-carboximidothioic acid methyl ester

: 1310682-63-3
N-(3,4-dichlorophenyl)-N'-(1-isopropyl-4-oxo-4,5-dihydro-1H-imidazol-2-yl)pyrrolidine-1-carboxamidine

Guidance literature:: With potassium carbonate; In propan-1-ol; Inert atmosphere; Reflux;
DOI:10.1021/jm200111g

Reference yield:

: 309942-79-8
pyrrolidine-1-carbothioic acid (3,4-dichlorophenyl)amide

: 1310682-63-3
N-(3,4-dichlorophenyl)-N'-(1-isopropyl-4-oxo-4,5-dihydro-1H-imidazol-2-yl)pyrrolidine-1-carboxamidine

Guidance literature:: Multi-step reaction with 2 steps

1.1: acetone / 4 h / 60 °C / Inert atmosphere

1.2: 25 °C / Alkaline conditions; Inert atmosphere

2.1: potassium carbonate / propan-1-ol / Inert atmosphere; Reflux

With potassium carbonate; In propan-1-ol; acetone;
DOI:10.1021/jm200111g

Reference yield:

: 1310682-72-4
1-isopropyl-2-methylsulfanyl-1,5-dihydroimidazol-4-one

: 1310682-63-3
N-(3,4-dichlorophenyl)-N'-(1-isopropyl-4-oxo-4,5-dihydro-1H-imidazol-2-yl)pyrrolidine-1-carboxamidine

Guidance literature:: Multi-step reaction with 2 steps

1: ammonia / methanol / Inert atmosphere; Heating

2: potassium carbonate / propan-1-ol / Inert atmosphere; Reflux

With ammonia; potassium carbonate; In methanol; propan-1-ol;
DOI:10.1021/jm200111g