1-bromo-α-phenyl-2-naphthalenemethanol

Base Information

• Chemical Name: 1-bromo-α-phenyl-2-naphthalenemethanol
• CAS No.: 114468-95-0
• Molecular Formula: C₁₇H₁₃BrO
• Molecular Weight: 313.194
• Mol file: 114468-95-0.mol

Synonyms:1-bromo-α-phenyl-2-naphthalenemethanol

Chemical Property of 1-bromo-α-phenyl-2-naphthalenemethanol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-bromo-α-phenyl-2-naphthalenemethanol

There total 1 articles about 1-bromo-α-phenyl-2-naphthalenemethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

1-bromo-2-naphthaldehyde (3378-82-3) + phenylmagnesium bromide (100-58-3) → 1-bromo-α-phenyl-2-naphthalenemethanol (114468-95-0)

Guidance literature:

In diethyl ether; for 4h; Ambient temperature;

DOI:10.1021/jo00248a009

Reference yield:

1-bromo-α-phenyl-2-naphthalenemethanol (114468-95-0) → (1-bromonaphthalen-2-yl)(phenyl)methanone

Guidance literature:

With manganese(IV) oxide; In dichloromethane; at 20 ℃; for 17.5h; Inert atmosphere;

DOI:10.1002/ejoc.201801537

Reference yield:

1-bromo-α-phenyl-2-naphthalenemethanol (114468-95-0) → 1-(1-bromonaphthalen-2-yl)-1-phenylethan-1-ol

Guidance literature:

Multi-step reaction with 2 steps

1: pyridinium chlorochromate; silica gel / dichloromethane / 3 h / 20 °C

2: tetrahydrofuran / 5 h / 0 - 20 °C

With silica gel; pyridinium chlorochromate; In tetrahydrofuran; dichloromethane;

DOI:10.1002/anie.202103428

upstream raw materials:

1-bromo-2-naphthaldehyde

phenylmagnesium bromide

Downstream raw materials:

cis-1,3-dihydro-1-hydroxy-3-phenylnaphtho<1,2-c>furan

methyl 1-phenyl-3-phenanthrenecarboxylate