4-(Piperidin-1-yl)-1,2,5-thiadiazol-3-ol

Base Information

Chemical Name:4-(Piperidin-1-yl)-1,2,5-thiadiazol-3-ol
CAS No.:891028-86-7
Molecular Formula:C₇H₁₁N₃OS
Molecular Weight:185.25
Hs Code.:
European Community (EC) Number:873-981-3
ChEMBL ID:CHEMBL1082514
Mol file:891028-86-7.mol

Synonyms:4-(piperidin-1-yl)-1,2,5-thiadiazol-3-ol;891028-86-7;4-piperidin-1-yl-1,2,5-thiadiazol-3-one;ChemDiv3_011854;CHEMBL1082514;SCHEMBL19584750;HMS1506K18;AKOS002307028;CCG-146427;IDI1_029412;EN300-233846;BRD-K97806623-001-01-4;F2167-4791;Z1551951278;4-(piperidin-1-yl)-2,3-dihydro-1,2,5-thiadiazol-3-one

Suppliers and Price of 4-(Piperidin-1-yl)-1,2,5-thiadiazol-3-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-(piperidin-1-yl)-1,2,5-thiadiazol-3-ol
50mg
$ 155.00

Total 1 raw suppliers

Chemical Property of 4-(Piperidin-1-yl)-1,2,5-thiadiazol-3-ol

Chemical Property:

XLogP3:0.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:185.06228316
Heavy Atom Count:12
Complexity:223

Purity/Quality:: 4-(piperidin-1-yl)-1,2,5-thiadiazol-3-ol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CCN(CC1)C2=NSNC2=O

Technology Process of 4-(Piperidin-1-yl)-1,2,5-thiadiazol-3-ol

There total 2 articles about 4-(Piperidin-1-yl)-1,2,5-thiadiazol-3-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 173053-54-8
3-(piperidin-1-yl)-4-chloro-1,2,5-thiadiazole

: 891028-86-7
3-hydroxy-4-(piperidin-1-yl)-1,2,5-thiadiazole

Guidance literature:: With potassium hydroxide; In water; dimethyl sulfoxide; Reflux;
DOI:10.1002/cmdc.201402453

Reference yield:

: 110-89-4
piperidine

: 891028-86-7
3-hydroxy-4-(piperidin-1-yl)-1,2,5-thiadiazole

Guidance literature:: Multi-step reaction with 2 steps

1: 110 - 120 °C

2: potassium hydroxide / dimethyl sulfoxide; water / Reflux

With potassium hydroxide; In water; dimethyl sulfoxide;
DOI:10.1002/cmdc.201402453

Reference yield: 88.0%

: 891028-86-7
3-hydroxy-4-(piperidin-1-yl)-1,2,5-thiadiazole

: 83-01-2
diphenylcarbamic chloride

: 4-(piperidin-1-yl)-1,2,5-thiadiazol-3-yl diphenylcarbamate

Guidance literature:: 3-hydroxy-4-(piperidin-1-yl)-1,2,5-thiadiazole; With potassium tert-butylate; In tetrahydrofuran; at 0 ℃;

diphenylcarbamic chloride; In tetrahydrofuran; at 20 - 25 ℃; Inert atmosphere;
DOI:10.1002/cmdc.201402453