N¹-<11-<(Benzyloxycarbonyl)amino>undecanoyl>-N⁴,N⁸-bis(toluol-4-sulfonyl)spermidin

Base Information

• Chemical Name: N¹-<11-<(Benzyloxycarbonyl)amino>undecanoyl>-N⁴,N⁸-bis(toluol-4-sulfonyl)spermidin
• CAS No.: 150671-88-8
• Molecular Formula: C₄₀H₅₈N₄O₇S₂
• Molecular Weight: 771.055
• Mol file: 150671-88-8.mol

Synonyms:N¹-<11-<(Benzyloxycarbonyl)amino>undecanoyl>-N⁴,N⁸-bis(toluol-4-sulfonyl)spermidin

Chemical Property of N¹-<11-<(Benzyloxycarbonyl)amino>undecanoyl>-N⁴,N⁸-bis(toluol-4-sulfonyl)spermidin

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N¹-<11-<(Benzyloxycarbonyl)amino>undecanoyl>-N⁴,N⁸-bis(toluol-4-sulfonyl)spermidin

There total 3 articles about N¹-<11-<(Benzyloxycarbonyl)amino>undecanoyl>-N⁴,N⁸-bis(toluol-4-sulfonyl)spermidin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

11-aminoundecanoic acid (2432-99-7,25587-80-8,84029-94-7) → N1-<11-<(Benzyloxycarbonyl)amino>undecanoyl>-N4,N8-bis(toluol-4-sulfonyl)spermidin (150671-88-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 78 percent / NaOH / H₂O / 0 °C

2: 1) 1,1'-carbonyldiimidazole / 1) THF, r.t., 2 h, 2) THF, r.t., 1 h

With sodium hydroxide; 1,1'-carbonyldiimidazole; In water;

DOI:10.1002/hlca.19930760304

Reference yield:

benzyl chloroformate (501-53-1,94274-21-2) → N1-<11-<(Benzyloxycarbonyl)amino>undecanoyl>-N4,N8-bis(toluol-4-sulfonyl)spermidin (150671-88-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 78 percent / NaOH / H₂O / 0 °C

2: 1) 1,1'-carbonyldiimidazole / 1) THF, r.t., 2 h, 2) THF, r.t., 1 h

With sodium hydroxide; 1,1'-carbonyldiimidazole; In water;

DOI:10.1002/hlca.19930760304

Reference yield:

11-<(Benzyloxycarbonyl)amino>undecansaeure (3422-91-1) + C21H31N3O4S2*C2H4O2 → N1-<11-<(Benzyloxycarbonyl)amino>undecanoyl>-N4,N8-bis(toluol-4-sulfonyl)spermidin (150671-88-8)

Guidance literature:

With 1,1'-carbonyldiimidazole; Yield given. Multistep reaction; 1) THF, r.t., 2 h, 2) THF, r.t., 1 h;

DOI:10.1002/hlca.19930760304

upstream raw materials:

11-<(Benzyloxycarbonyl)amino>undecansaeure

11-aminoundecanoic acid

benzyl chloroformate

Downstream raw materials:

N¹-(11-Aminoundecanoyl)-N⁴,N⁸-bis(toluol-4-sulfonyl)spermidin

(RS)-N¹-<11-<amino>undecanoyl>-N⁴,N⁸-bis(toluol-4-sulfonyl)spermidin

(RS)-N¹-<11-<alanyl>amino>undecanoyl>-N⁴,N⁸-bis(toluol-4-sulfonyl)spermidin

(RS)-N¹-<11-<alanyl>amino>undecanoyl>-N⁴,N⁸-bis(toluol-4-sulfonyl)spermidin