C₁₆H₁₂FNO

Base Information

• Chemical Name: C₁₆H₁₂FNO
• CAS No.: 1584688-08-3
• Molecular Formula: C₁₆H₁₂FNO
• Molecular Weight: 253.276
• Mol file: 1584688-08-3.mol

Synonyms:C₁₆H₁₂FNO

Chemical Property of C₁₆H₁₂FNO

Chemical Property:

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Technology Process of C₁₆H₁₂FNO

There total 1 articles about C₁₆H₁₂FNO which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

2-methylchlorobenzene (95-49-8) + 5-(4-fluorophenyl)-1,3-oxazole (128101-19-9) → C16H12FNO (1584688-08-3)

Guidance literature:

With PdCl₂(C₃H₃N₂(CH₃))(C₃H₂N₂(C₆H₃(C₃H₇)2)2); lithium tert-butoxide; In toluene; at 130 ℃; for 18h; Inert atmosphere;

DOI:10.1021/ol500531m

upstream raw materials:

2-methylchlorobenzene

5-(4-fluorophenyl)-1,3-oxazole