methotrexate-GFLG

Base Information

Chemical Name:methotrexate-GFLG
CAS No.:1204326-25-9
Molecular Formula:C₃₉H₄₈N₁₂O₉
Molecular Weight:828.885
Hs Code.:

Synonyms:methotrexate-GFLG

Suppliers and Price of methotrexate-GFLG

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of methotrexate-GFLG

Chemical Property:

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Technology Process of methotrexate-GFLG

There total 1 articles about methotrexate-GFLG which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 122856-33-1
methotrexate N-hydroxysuccinimde ester

: 104845-49-0
glycine-phenylananine-leucine-glycine

: 1204326-25-9
methotrexate-GFLG

Guidance literature:: With triethylamine; In dimethyl sulfoxide; at 20 ℃; Darkness; Inert atmosphere;
DOI:10.1021/bm900853z

Reference yield: 60.0%

: 6066-82-6
1-hydroxy-pyrrolidine-2,5-dione

: 1204326-25-9
methotrexate-GFLG

: 1204326-26-0
methotrexate-GFLG-NHS

Guidance literature:: methotrexate-GFLG; With dicyclohexyl-carbodiimide; In dimethyl sulfoxide; at 20 ℃; for 2h;

1-hydroxy-pyrrolidine-2,5-dione; With dmap; In dimethyl sulfoxide; at 40 ℃; Darkness; Inert atmosphere;
DOI:10.1021/bm900853z