(S)-N₄-(5-cyclopropyl-1H-pyrazol-3-yl)-N₂-[1-(4-fluoro-phenyl)-ethyl]pyridine-2,4,5-triamine

Base Information

• Chemical Name: (S)-N₄-(5-cyclopropyl-1H-pyrazol-3-yl)-N₂-[1-(4-fluoro-phenyl)-ethyl]pyridine-2,4,5-triamine
• CAS No.: 907203-90-1
• Molecular Formula: C₁₉H₂₁FN₆
• Molecular Weight: 352.414

Synonyms:(S)-N₄-(5-cyclopropyl-1H-pyrazol-3-yl)-N₂-[1-(4-fluoro-phenyl)-ethyl]pyridine-2,4,5-triamine

Chemical Property of (S)-N₄-(5-cyclopropyl-1H-pyrazol-3-yl)-N₂-[1-(4-fluoro-phenyl)-ethyl]pyridine-2,4,5-triamine

Chemical Property:

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Technology Process of (S)-N₄-(5-cyclopropyl-1H-pyrazol-3-yl)-N₂-[1-(4-fluoro-phenyl)-ethyl]pyridine-2,4,5-triamine

There total 1 articles about (S)-N₄-(5-cyclopropyl-1H-pyrazol-3-yl)-N₂-[1-(4-fluoro-phenyl)-ethyl]pyridine-2,4,5-triamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(S)-N4-(5-cyclopropyl-1H-pyrazol-3-yl)-N2-[1-(4-fluoro-phenyl)-ethyl]-5-nitro-pyridine-2,4-diamine (907203-91-2) → (S)-N4-(5-cyclopropyl-1H-pyrazol-3-yl)-N2-[1-(4-fluoro-phenyl)-ethyl]pyridine-2,4,5-triamine (907203-90-1)

Guidance literature:

(S)-N₄-(5-cyclopropyl-1H-pyrazol-3-yl)-N₂-[1-(4-fluoro-phenyl)-ethyl]-5-nitro-pyridine-2,4-diamine; With ammonium chloride; zinc; In tetrahydrofuran; methanol; water; at 25 ℃; for 2h;

With ammonium acetate; In tetrahydrofuran; methanol; water; at 25 ℃; for 0.5h;

Reference yield: 60.0%

(S)-N4-(5-cyclopropyl-1H-pyrazol-3-yl)-N2-[1-(4-fluoro-phenyl)-ethyl]pyridine-2,4,5-triamine (907203-90-1) + formamidine acetic acid (3473-63-0) → 1-(5-cyclopropyl-1H-pyrazol-3-yl)-N-((S)-1-(4-fluorophenyl)ethyl)-1H-imidazo[4,5-c]pyridin-6-amine

Guidance literature:

In ethanol; for 2h; Heating / reflux;

upstream raw materials:

(S)-N₄-(5-cyclopropyl-1H-pyrazol-3-yl)-N₂-[1-(4-fluoro-phenyl)-ethyl]-5-nitro-pyridine-2,4-diamine

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