Formamidine acetate (1:1)

Base Information

• Chemical Name: Formamidine acetate (1:1)
• CAS No.: 3473-63-0
• Deprecated CAS: 146797-05-9,40730-94-7,87667-19-4
• Molecular Formula: C2H4O2^.CH4N2
• Molecular Weight: 104.109
• Hs Code.: 29252000
• DSSTox Substance ID: DTXSID3063047
• Mol file: 3473-63-0.mol

Synonyms:Formamidine acetate (1:1);DTXSID3063047

Chemical Property of Formamidine acetate (1:1)

Chemical Property:

• Appearance/Colour: white to light yellow crystalline powder
• Vapor Pressure: 0.00686mmHg at 25°C
• Melting Point: 158-161 °C (dec.)(lit.)
• Boiling Point: 117.1 °C at 760 mmHg
• Flash Point: 40 °C
• PSA: 87.17000
• Density: 1.124 g/cm³
• LogP: 0.44310
• Storage Temp.: -20°C
• Sensitive.: Hygroscopic
• Solubility.: 832g/l
• Water Solubility.: 832 g/L (21 ºC)
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 104.058577502
• Heavy Atom Count: 7
• Complexity: 33

Purity/Quality:

99% ^*data from raw suppliers

Formamidine Acetate ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 43-36/37/38
• Safety Statements: 36/37-37/39-26-36/37/39-27

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CC(=O)[O-].C(=[NH2+])N
• Uses: Formamidine acetate is used as an intermediate in the synthesis of active pharmaceutical ingredients. It is also used as a condensing agent for the preparation of pyrimidine and imidazole heterocycles. Formamidine acetate salt is widely used in the preparation of formamidinium lead triiodide (FAPbI3) perovskites for perovskite solar cells. It is also used in the synthesis of formamidinium lead bromide nanocrystals for use as emitters in display applications.

Technology Process of Formamidine acetate (1:1)

There total 3 articles about Formamidine acetate (1:1) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

orthoformic acid triethyl ester (122-51-0) → formamidine acetic acid (3473-63-0)

Guidance literature:

With ammonia; acetic acid;

Reference yield: 63.0%

CYANAMID (420-04-2) + acetic acid (64-19-7,77671-22-8) → formamidine acetic acid (3473-63-0)

Guidance literature:

With 5%-palladium/activated carbon; hydrogen; In water; for 3.5h;

DOI:10.1039/d1gc00700a

Reference yield:

acetic acid (64-19-7,77671-22-8) + orthoformic acid triethyl ester (122-51-0) → formamidine acetic acid (3473-63-0)

Guidance literature:

With ammonia; Reflux;

upstream raw materials:

orthoformic acid triethyl ester

acetic acid

CYANAMID

Downstream raw materials:

7-Amino-oxazolo<5,4-d>pyrimidin

6-ethyl-4(3H)-pyrimidinone

4-Aminoquinazoline

pyrrolo[2,1-f][1,2,4]triazin-4-amine

Refernces

• 1、 -. "Method for producing formamidine acetate". Sheet 0056; 0057. . Retrieved 2018/10/24.