ethyl allyl-(2-allyl-4-chloro-phenyl)carbamate

Base Information

• Chemical Name: ethyl allyl-(2-allyl-4-chloro-phenyl)carbamate
• CAS No.: 1316312-70-5
• Molecular Formula: C₁₅H₁₈ClNO₂
• Molecular Weight: 279.766
• Mol file: 1316312-70-5.mol

Synonyms:ethyl allyl-(2-allyl-4-chloro-phenyl)carbamate

Chemical Property of ethyl allyl-(2-allyl-4-chloro-phenyl)carbamate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of ethyl allyl-(2-allyl-4-chloro-phenyl)carbamate

There total 3 articles about ethyl allyl-(2-allyl-4-chloro-phenyl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

C12H14ClN (1118507-33-7) + chloroformic acid ethyl ester (541-41-3) → ethyl allyl-(2-allyl-4-chloro-phenyl)carbamate (1316312-70-5)

Guidance literature:

With pyridine; In dichloromethane; at 0 - 25 ℃; for 24h;

DOI:10.1002/ejoc.201100040

Reference yield:

N,N-diallyl-4-chlorobenzenamine (30438-94-9) → ethyl allyl-(2-allyl-4-chloro-phenyl)carbamate (1316312-70-5)

Guidance literature:

Multi-step reaction with 2 steps

1: boron trifluoride diethyl etherate / 5,5-dimethyl-1,3-cyclohexadiene / 135 - 140 °C / Inert atmosphere

2: pyridine / dichloromethane / 24 h / 0 - 25 °C

With pyridine; boron trifluoride diethyl etherate; In 5,5-dimethyl-1,3-cyclohexadiene; dichloromethane; 1: Claisen rearrangement;

DOI:10.1002/ejoc.201100040

Reference yield:

4-chloro-aniline (106-47-8) → ethyl allyl-(2-allyl-4-chloro-phenyl)carbamate (1316312-70-5)

Guidance literature:

Multi-step reaction with 3 steps

1: sodium hydride / N,N-dimethyl-formamide / 4 h / 0 - 25 °C

2: boron trifluoride diethyl etherate / 5,5-dimethyl-1,3-cyclohexadiene / 135 - 140 °C / Inert atmosphere

3: pyridine / dichloromethane / 24 h / 0 - 25 °C

With pyridine; boron trifluoride diethyl etherate; sodium hydride; In 5,5-dimethyl-1,3-cyclohexadiene; dichloromethane; N,N-dimethyl-formamide; 2: Claisen rearrangement;

DOI:10.1002/ejoc.201100040

upstream raw materials:

C₁₂H₁₄ClN

chloroformic acid ethyl ester

N,N-diallyl-4-chlorobenzenamine

4-chloro-aniline

Downstream raw materials:

ethyl (2-buta-1,3-dienyl-4-chlorophenyl)carbamate

ethyl 6-chloro-2-methyl-2H-quinoline-1-carboxylate