N-(1-benzylpiperidin-4-yl)-2-(2-bromo-5-fluorophenyl)-2-methyl-propanamide

Base Information

Chemical Name:N-(1-benzylpiperidin-4-yl)-2-(2-bromo-5-fluorophenyl)-2-methyl-propanamide
CAS No.:1240702-78-6
Molecular Formula:C₂₂H₂₆BrFN₂O
Molecular Weight:433.364
Hs Code.:

Synonyms:N-(1-benzylpiperidin-4-yl)-2-(2-bromo-5-fluorophenyl)-2-methyl-propanamide

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Chemical Property of N-(1-benzylpiperidin-4-yl)-2-(2-bromo-5-fluorophenyl)-2-methyl-propanamide

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Technology Process of N-(1-benzylpiperidin-4-yl)-2-(2-bromo-5-fluorophenyl)-2-methyl-propanamide

There total 1 articles about N-(1-benzylpiperidin-4-yl)-2-(2-bromo-5-fluorophenyl)-2-methyl-propanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 33.0%

: 50541-93-0
4-amino-1-benzylpiperidine

: 1240702-77-5
2-(2-bromo-5-fluorophenyl)-2-methylpropanoic acid

: 1240702-78-6
N-(1-benzylpiperidin-4-yl)-2-(2-bromo-5-fluorophenyl)-2-methyl-propanamide

Guidance literature:: 2-(2-bromo-5-fluorophenyl)-2-methylpropanoic acid; With bis(trichloromethyl) carbonate; triethylamine; In tetrahydrofuran; at 20 ℃; for 0.5h;

4-amino-1-benzylpiperidine; With triethylamine; In tetrahydrofuran; at 20 ℃;

Reference yield: 76.0%

: 1240702-78-6
N-(1-benzylpiperidin-4-yl)-2-(2-bromo-5-fluorophenyl)-2-methyl-propanamide

: 1240702-80-0
1-(1-benzylpiperidin-4-yl)-5-fluoro-3.3-dimethylindolin-2-one

Guidance literature:: With potassium carbonate; phenylboronic acid; palladium diacetate; XPhos; In tert-butyl alcohol; for 14h; Reflux; Inert atmosphere;