3-(3-bromo-10-(4-(hexyloxy)phenyl)-10H-phenothiazin-7-yl)-10-(4-(hexyloxy)phenyl)-10H-phenothiazine

Base Information

• Chemical Name: 3-(3-bromo-10-(4-(hexyloxy)phenyl)-10H-phenothiazin-7-yl)-10-(4-(hexyloxy)phenyl)-10H-phenothiazine
• CAS No.: 1403613-84-2
• Molecular Formula: C₄₈H₄₇BrN₂O₂S₂
• Molecular Weight: 827.949
• Mol file: 1403613-84-2.mol

Synonyms:3-(3-bromo-10-(4-(hexyloxy)phenyl)-10H-phenothiazin-7-yl)-10-(4-(hexyloxy)phenyl)-10H-phenothiazine

Chemical Property of 3-(3-bromo-10-(4-(hexyloxy)phenyl)-10H-phenothiazin-7-yl)-10-(4-(hexyloxy)phenyl)-10H-phenothiazine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-(3-bromo-10-(4-(hexyloxy)phenyl)-10H-phenothiazin-7-yl)-10-(4-(hexyloxy)phenyl)-10H-phenothiazine

There total 2 articles about 3-(3-bromo-10-(4-(hexyloxy)phenyl)-10H-phenothiazin-7-yl)-10-(4-(hexyloxy)phenyl)-10H-phenothiazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

{10-[4-(hexyloxy)phenyl]-10H-phenothiazin-3-yl}boronic acid + 3,7-dibromo-10-(4-(hexyloxy)phenyl)-10H-phenothiazine (1403613-83-1) → 3-(3-bromo-10-(4-(hexyloxy)phenyl)-10H-phenothiazin-7-yl)-10-(4-(hexyloxy)phenyl)-10H-phenothiazine (1403613-84-2)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate; In tetrahydrofuran; water; toluene; at 60 ℃; for 12h; Inert atmosphere;

DOI:10.1039/c2jm35556f

Reference yield:

C30H38BNO3S → 3-(3-bromo-10-(4-(hexyloxy)phenyl)-10H-phenothiazin-7-yl)-10-(4-(hexyloxy)phenyl)-10H-phenothiazine (1403613-84-2)

Guidance literature:

Multi-step reaction with 2 steps

1: hydrogenchloride; water / tetrahydrofuran; hexane / 1 h / 20 °C / Inert atmosphere

2: potassium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾ / tetrahydrofuran; water; toluene / 12 h / 60 °C / Inert atmosphere

With hydrogenchloride; tetrakis(triphenylphosphine) palladium⁽⁰⁾; water; potassium carbonate; In tetrahydrofuran; hexane; water; toluene; 2: |Suzuki-Miyaura Coupling;

DOI:10.1039/c2jm35556f

Reference yield: 82.0%

3-(3-bromo-10-(4-(hexyloxy)phenyl)-10H-phenothiazin-7-yl)-10-(4-(hexyloxy)phenyl)-10H-phenothiazine (1403613-84-2) + N,N-dimethyl-formamide (68-12-2,33513-42-7) → 10-(4-(hexyloxy)phenyl)-7-(10-(4-(hexyloxy)phenyl)-10H-phenothiazin-7-yl)-10H-phenothiazine-3-carbaldehyde (1403613-85-3)

Guidance literature:

3-(3-bromo-10-(4-(hexyloxy)phenyl)-10H-phenothiazin-7-yl)-10-(4-(hexyloxy)phenyl)-10H-phenothiazine; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 1h; Inert atmosphere;

N,N-dimethyl-formamide; In tetrahydrofuran; hexane; at -78 ℃; for 6h; Inert atmosphere;

DOI:10.1039/c2jm35556f

upstream raw materials:

3,7-dibromo-10-(4-(hexyloxy)phenyl)-10H-phenothiazine

Downstream raw materials:

10-(4-(hexyloxy)phenyl)-7-(10-(4-(hexyloxy)phenyl)-10H-phenothiazin-7-yl)-10H-phenothiazine-3-carbaldehyde