R-3-[1-((1S)-4-benzyl-2-oxo-oxazolidin-3-yl)-methanoyl]-dadecanoic acid tert-butyl ester

Base Information

Chemical Name:R-3-[1-((1S)-4-benzyl-2-oxo-oxazolidin-3-yl)-methanoyl]-dadecanoic acid tert-butyl ester
CAS No.:245652-05-5
Molecular Formula:C₂₇H₄₁NO₅
Molecular Weight:459.626
Hs Code.:

Synonyms:R-3-[1-((1S)-4-benzyl-2-oxo-oxazolidin-3-yl)-methanoyl]-dadecanoic acid tert-butyl ester

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of R-3-[1-((1S)-4-benzyl-2-oxo-oxazolidin-3-yl)-methanoyl]-dadecanoic acid tert-butyl ester

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of R-3-[1-((1S)-4-benzyl-2-oxo-oxazolidin-3-yl)-methanoyl]-dadecanoic acid tert-butyl ester

There total 5 articles about R-3-[1-((1S)-4-benzyl-2-oxo-oxazolidin-3-yl)-methanoyl]-dadecanoic acid tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 5292-43-3
bromoacetic acid tert-butyl ester

: 334756-88-6
(S)-4-benzyl-3-undecanoyloxazolidine-2-one

: 245652-05-5
R-3-[1-((1S)-4-benzyl-2-oxo-oxazolidin-3-yl)-methanoyl]-dadecanoic acid tert-butyl ester

Guidance literature:: With sodium hexamethyldisilazane; at -78 ℃;
DOI:10.1016/S0960-894X(96)00602-6

Reference yield:

: 17746-05-3
undecanoyl chloride

: 245652-05-5
R-3-[1-((1S)-4-benzyl-2-oxo-oxazolidin-3-yl)-methanoyl]-dadecanoic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) n-BuLi / 1.) THF, hexane, -78 deg C, 25 min, 2.) THF, hexane, from -78 deg C to RT

2: LDA / tetrahydrofuran; hexane / -78 - 20 °C

With n-butyllithium; lithium diisopropyl amide; In tetrahydrofuran; hexane;
DOI:10.1021/jm970404a

Reference yield:

: 90719-32-7
(S)-4-Benzyl-2-oxazolidinone

: 245652-05-5
R-3-[1-((1S)-4-benzyl-2-oxo-oxazolidin-3-yl)-methanoyl]-dadecanoic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) n-BuLi / 1.) THF, hexane, -78 deg C, 25 min, 2.) THF, hexane, from -78 deg C to RT

2: LDA / tetrahydrofuran; hexane / -78 - 20 °C

With n-butyllithium; lithium diisopropyl amide; In tetrahydrofuran; hexane;
DOI:10.1021/jm970404a