methyl 1-(dimethoxymethyl)-9-(3,4,5-trimethoxybenzyl)-9H-carboline-3-carboxylate

Base Information

• Chemical Name: methyl 1-(dimethoxymethyl)-9-(3,4,5-trimethoxybenzyl)-9H-carboline-3-carboxylate
• CAS No.: 1379826-11-5
• Molecular Formula: C₂₆H₂₈N₂O₇
• Molecular Weight: 480.518
• Mol file: 1379826-11-5.mol

Synonyms:methyl 1-(dimethoxymethyl)-9-(3,4,5-trimethoxybenzyl)-9H-carboline-3-carboxylate

Chemical Property of methyl 1-(dimethoxymethyl)-9-(3,4,5-trimethoxybenzyl)-9H-carboline-3-carboxylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 1-(dimethoxymethyl)-9-(3,4,5-trimethoxybenzyl)-9H-carboline-3-carboxylate

There total 1 articles about methyl 1-(dimethoxymethyl)-9-(3,4,5-trimethoxybenzyl)-9H-carboline-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

3,4,5-trimethoxybenzyl bromide (21852-50-6) + 1-dimethoxymethyl-9H-β-carboline-3-carboxylic acid methyl ester (129609-50-3) → methyl 1-(dimethoxymethyl)-9-(3,4,5-trimethoxybenzyl)-9H-carboline-3-carboxylate (1379826-11-5)

Guidance literature:

1-dimethoxymethyl-9H-β-carboline-3-carboxylic acid methyl ester; With caesium carbonate; In N,N-dimethyl-formamide; for 0.25h;

3,4,5-trimethoxybenzyl bromide; In N,N-dimethyl-formamide; for 1h;

DOI:10.1002/ejoc.201200068

Reference yield: 90.0%

methyl 1-(dimethoxymethyl)-9-(3,4,5-trimethoxybenzyl)-9H-carboline-3-carboxylate (1379826-11-5) → methyl 9-(3,4,5-trimethoxybenzyl)-1-formyl-9H-β-carboline-3-carboxylate (1379826-21-7)

Guidance literature:

With acetic acid; In water; at 90 ℃; for 0.75h;

DOI:10.1002/ejoc.201200068

Reference yield: 86.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + methyl 1-(dimethoxymethyl)-9-(3,4,5-trimethoxybenzyl)-9H-carboline-3-carboxylate (1379826-11-5) + 4-chloro-aniline (106-47-8) → 2-(4-chlorophenyl)-5-(methoxycarbonyl)-11-(3,4,5-trimethoxybenzyl)-2,11-dihydroimidazo[1′,5′:1,2]pyrido[3,4-b]-indol-4-ium chloride

Guidance literature:

formaldehyd; 4-chloro-aniline; With acetyl chloride; In ethanol; at 0 ℃; for 0.333333h;

methyl 1-(dimethoxymethyl)-9-(3,4,5-trimethoxybenzyl)-9H-carboline-3-carboxylate; In ethanol; at 20 ℃; for 12h;

DOI:10.1021/acs.jmedchem.5b00016

upstream raw materials:

3,4,5-trimethoxybenzyl bromide

1-dimethoxymethyl-9H-β-carboline-3-carboxylic acid methyl ester

Downstream raw materials:

methyl 9-(3,4,5-trimethoxybenzyl)-1-formyl-9H-β-carboline-3-carboxylate

methyl 1-(hydroxy(6-oxocyclohex-1-enyl)methyl)-9-(3,4,5-trimethoxybenzyl)-9H-pyrido[3,4-b]indole-3-carboxylate

methyl 12-(3,4,5-trimethoxybenzyl)-1-oxo-2,3,4,12-tetrahydro-1H-benzo[2,3]indolizino[8,7-b]indole-6-carboxylate

methyl 1-(hydroxymethyl)-9-(3,4,5-trimethoxybenzyl)-9H-β-carboline-3-carboxylate