4-Oxo-4-<4-(trimethylsiloxy)-3-cyclohexenyl>butansaeure-methylester

Base Information

• Chemical Name: 4-Oxo-4-<4-(trimethylsiloxy)-3-cyclohexenyl>butansaeure-methylester
• CAS No.: 106799-45-5
• Molecular Formula: C₁₄H₂₄O₄Si
• Molecular Weight: 284.428
• Mol file: 106799-45-5.mol

Synonyms:4-Oxo-4-<4-(trimethylsiloxy)-3-cyclohexenyl>butansaeure-methylester

Chemical Property of 4-Oxo-4-<4-(trimethylsiloxy)-3-cyclohexenyl>butansaeure-methylester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-Oxo-4-<4-(trimethylsiloxy)-3-cyclohexenyl>butansaeure-methylester

There total 1 articles about 4-Oxo-4-<4-(trimethylsiloxy)-3-cyclohexenyl>butansaeure-methylester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

4-oxo-hex-5-enoic acid methyl ester (23684-13-1) + 2-trimethylsilyloxy-1,3-butadiene (38053-91-7) → 4-Oxo-4-<4-(trimethylsiloxy)-3-cyclohexenyl>butansaeure-methylester (106799-45-5)

Guidance literature:

In toluene; for 16h; Heating;

Reference yield: 92.0%

4-Oxo-4-<4-(trimethylsiloxy)-3-cyclohexenyl>butansaeure-methylester (106799-45-5) → 4-Oxo-4-(4-oxocyclohexyl)butansaeure-methylester (106799-46-6)

Guidance literature:

With triethylamine.2.5HF; In dichloromethane; for 2h; Ambient temperature;

Reference yield:

4-Oxo-4-<4-(trimethylsiloxy)-3-cyclohexenyl>butansaeure-methylester (106799-45-5) → rac-Norbisabolid (86532-06-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 92 percent / NEt₃ * 2.5 HF / CH₂Cl₂ / 2 h / Ambient temperature

With triethylamine.2.5HF; In dichloromethane;

upstream raw materials:

4-oxo-hex-5-enoic acid methyl ester

2-trimethylsilyloxy-1,3-butadiene

Downstream raw materials:

4-Oxo-4-(4-oxocyclohexyl)butansaeure-methylester

rac-Norbisabolid