3,4-dimethoxy-6-methyl-2-(4-methylpent-4-enyl)phenoxyltetrahydropyran

Base Information

• Chemical Name: 3,4-dimethoxy-6-methyl-2-(4-methylpent-4-enyl)phenoxyltetrahydropyran
• CAS No.: 192124-41-7
• Molecular Formula: C₂₀H₃₀O₄
• Molecular Weight: 334.456
• Mol file: 192124-41-7.mol

Synonyms:3,4-dimethoxy-6-methyl-2-(4-methylpent-4-enyl)phenoxyltetrahydropyran

Chemical Property of 3,4-dimethoxy-6-methyl-2-(4-methylpent-4-enyl)phenoxyltetrahydropyran

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3,4-dimethoxy-6-methyl-2-(4-methylpent-4-enyl)phenoxyltetrahydropyran

There total 3 articles about 3,4-dimethoxy-6-methyl-2-(4-methylpent-4-enyl)phenoxyltetrahydropyran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3,4-dihydro-2H-pyran (110-87-2) → 3,4-dimethoxy-6-methyl-2-(4-methylpent-4-enyl)phenoxyltetrahydropyran (192124-41-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 92 percent / PPTS / CH₂Cl₂

2: 1.) n-BuLi, 2.) HMPA / 1.) THF, 0 deg C -> rt, 2 h, 2.) THF, 0 deg C

With N,N,N,N,N,N-hexamethylphosphoric triamide; n-butyllithium; pyridinium p-toluenesulfonate; In dichloromethane;

DOI:10.1016/S0040-4020(97)00581-4

Reference yield:

2-hydroxy-4,5-dimethoxytoluene (72312-07-3) → 3,4-dimethoxy-6-methyl-2-(4-methylpent-4-enyl)phenoxyltetrahydropyran (192124-41-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 92 percent / PPTS / CH₂Cl₂

2: 1.) n-BuLi, 2.) HMPA / 1.) THF, 0 deg C -> rt, 2 h, 2.) THF, 0 deg C

With N,N,N,N,N,N-hexamethylphosphoric triamide; n-butyllithium; pyridinium p-toluenesulfonate; In dichloromethane;

DOI:10.1016/S0040-4020(97)00581-4

Reference yield:

5-bromo-2-methyl-1-pentene (41182-50-7) + 3,4-dimethoxy-6-methylphenoxyltetrahydropyran (192124-38-2) → 3,4-dimethoxy-6-methyl-2-(4-methylpent-4-enyl)phenoxyltetrahydropyran (192124-41-7)

Guidance literature:

With N,N,N,N,N,N-hexamethylphosphoric triamide; n-butyllithium; Yield given. Multistep reaction; 1.) THF, 0 deg C -> rt, 2 h, 2.) THF, 0 deg C;

DOI:10.1016/S0040-4020(97)00581-4

upstream raw materials:

5-bromo-2-methyl-1-pentene

3,4-dimethoxy-6-methylphenoxyltetrahydropyran

3,4-dihydro-2H-pyran

2-hydroxy-4,5-dimethoxytoluene

Downstream raw materials:

3,4,4-trimethoxy-6-methyl-2-(4-methylpent-4-enyl)cyclohexa-2,5-dienone

3,4-Dimethoxy-6-methyl-2-(4-methyl-pent-4-enyl)-phenol