72312-07-3

Basic information

• Product Name: Phenol, 4,5-dimethoxy-2-methyl-
• CAS NO: 72312-07-3
• Molecular Formula: C9H12O3
• Molecular Weight: 168.192
• Mol File: 72312-07-3.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Phenol, 4,5-dimethoxy-2-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Phenol, 4,5-dimethoxy-2-methyl-(72312-07-3)
• EPA Substance Registry System: Phenol, 4,5-dimethoxy-2-methyl-(72312-07-3)

Safety Data

• Hazardous Substances Data: 72312-07-3(Hazardous Substances Data)

Upstream product

• 563-79-1 2,3-Dimethyl-2-butene 
• 72312-08-4 2-methyl-4,4,5-trimethoxycyclohexa-2,5-dienone 
• 7721-61-1 2-methyl-4-methoxy-5-hydroxybenzaldehyde 
• 93-51-6 2-Methoxy-4-methylphenol 
• 7721-62-2 4,5-dimethoxy-2-methylbenzaldehyde 
• 765-47-9 1,2-dimethylcyclopentene 

Downstream Products

• 192124-82-6 3,4-Dimethoxy-6-methyl-2-pent-4-enyl-phenol 
• 192124-70-2 3,4-Dimethoxy-6-methyl-2-(4-methyl-pent-4-enyl)-phenol 
• 192124-03-1 3,4,4-trimethoxy-6-methyl-2-(pent-4-enyl)cyclohexa-2,5-dienone 
• 192124-46-2 3,4,4-trimethoxy-6-methyl-2-(4-methylpent-4-enyl)cyclohexa-2,5-dienone 
• 192123-89-0 3,4-dimethoxy-6-methyl-2-(pent-4-enyl)phenoxytetrahydropyran 
• 192124-41-7 3,4-dimethoxy-6-methyl-2-(4-methylpent-4-enyl)phenoxyltetrahydropyran 
• 41410-53-1 (+/-)-gymnomitrol 
• 192124-38-2 3,4-dimethoxy-6-methylphenoxyltetrahydropyran 
• 14894-74-7 1,2,4-trimethoxy-5-methylbenzene 
• 614-13-1 2-methoxy-5-methyl-1,4-benzoquinone 
• 72312-08-4 2-methyl-4,4,5-trimethoxycyclohexa-2,5-dienone 

Relevant articles and documents

INTRODUCTION OF A HYDROXYL GROUP INTO THE CREOSOL MOLECULE

The introduction of a hydroxyl group into the molecule of 2-methoxy-4-methylphenol through Rieche formylation and Baeyer-Villiger oxidation was investigated.With dichloromethyl methyl ether meta-formylation of creosol occurs.

A synthesis of gymnomitrol

Condensation of 1,2 - dimethylcyclopentene 10 with 2 - methyl - 4,4, 5 - trimethoxycyclohexa - 2,5 -dienone 7 in methylene chloride - nitromethane with added stannic chloride gave a mixture of the two diastereomeric bicycle[3.2.1]octanes 13 and 14 by ionic [4+2]cycloaddition. After selective reduction of the saturated carbonyl group with sodium borohydride, and hydrogenation of the double bond the two epimers 18 and 20 (ratio 3.3:1) were separable by chromatography. Protection of the hydroxy group in 18 with dihydropyran and, reduction of the α-methoxyketone 19 with calcium in liquid ammonia gave ketone 21. Gymnomitrol 1 was then prepared by Wittig olefination followed by deprotection of the hydroxy group.