1,2-DIBROMO-4,5-(METHYLENEDIOXY)BENZENE

Base Information

• Chemical Name: 1,2-DIBROMO-4,5-(METHYLENEDIOXY)BENZENE
• CAS No.: 5279-32-3
• Molecular Formula: C7H4Br2O2
• Molecular Weight: 279.916
• Hs Code.: 2932999099
• Mol file: 5279-32-3.mol

Synonyms:4,5-Methylenedioxy-1,2-dibromobenzene;1,2-Dibromo-4,5-methylenedioxybenzene;

Chemical Property of 1,2-DIBROMO-4,5-(METHYLENEDIOXY)BENZENE

Chemical Property:

• Appearance/Colour: White to cream Solid
• Vapor Pressure: 0.00281mmHg at 25°C
• Melting Point: 83-85 °C
• Refractive Index: 1.638
• Boiling Point: 294.7 °C at 760 mmHg
• Flash Point: 118.1 °C
• PSA: 18.46000
• Density: 2.104 g/cm³
• LogP: 2.94030
• Storage Temp.: Inert atmosphere,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

5,6-Dibromo-1,3-benzodioxole >98.0%(GC) ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Safety Statements: 22-24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Technology Process of 1,2-DIBROMO-4,5-(METHYLENEDIOXY)BENZENE

There total 12 articles about 1,2-DIBROMO-4,5-(METHYLENEDIOXY)BENZENE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

1,2-(methylenedioxy)-4-bromobenzene (2635-13-4) → 5,6-dibromo-1,3-benzodioxole (5279-32-3)

Guidance literature:

With bromine; In dichloromethane; at -15 - 25 ℃; regioselective reaction; Inert atmosphere;

DOI:10.1002/ejoc.201501503

Reference yield: 78.0%

Methylenedioxybenzene (274-09-9) → 5,6-dibromo-1,3-benzodioxole (5279-32-3)

Guidance literature:

With bromine; In dichloromethane; at 0 - 20 ℃;

DOI:10.1002/anie.202004444

Reference yield: 75.0%

chlorobromomethane (74-97-5) + 4,5-dibromobenzene-1,2-diol (2563-26-0) → 5,6-dibromo-1,3-benzodioxole (5279-32-3)

Guidance literature:

With caesium carbonate; In N,N-dimethyl-formamide; at 110 ℃; for 3h;

DOI:10.1002/anie.200603945

upstream raw materials:

piperonal

Piperonylic acid

Methylenedioxybenzene

chlorobromomethane

Downstream raw materials:

Methylenedioxybenzene

5-bromo-6-(4-methylsulfanyl-phenyl)-benzo[1,3]dioxole

5-(3,5-difluoro-phenyl)-6-(4-methylsulfanyl-phenyl)-benzo[1,3]dioxole

benzo[1,3]dioxol-4-yl-methanol