2563-26-0

Basic information

• Product Name: 4,5-Dibromo-1,2-benzenediol
• Synonyms: 4 5-DIBROMOBENZENE-1 2-DIOL 90% TECH;4,5-DIBROMOBENZENE-1,2-DIOL, 90% tech grade;4,5-Dibromo-1,2-Benzenediol;1,2-BENZENEDIOL,4,5-DIBROMO-;4,5-dibromopyrocatechol;550248_SIAL;Benzen-1,2-diol, 4,5-dibromo-;NSC10858
• CAS NO: 2563-26-0
• Molecular Formula: C₆H₄Br₂O₂
• Molecular Weight: 267.9
• Mol File: 2563-26-0.mol

Chemical Properties

• Melting Point: 111-116°C (lit.)
• Boiling Point: 328.5 °C at 760 mmHg
• Flash Point: 152.5 °C
• Appearance: /
• Density: 2.257g/cm³
• Vapor Pressure: 9.89E-05mmHg at 25°C
• Refractive Index: 1.69
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 7.98±0.23(Predicted)
• CAS DataBase Reference: 4,5-Dibromo-1,2-benzenediol(CAS DataBase Reference)
• NIST Chemistry Reference: 4,5-Dibromo-1,2-benzenediol(2563-26-0)
• EPA Substance Registry System: 4,5-Dibromo-1,2-benzenediol(2563-26-0)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• Hazardous Substances Data: 2563-26-0(Hazardous Substances Data)

Usage

Uses

4,?5-?Dibromobenzene-?1,?2-?diol is a dye. Dyes and metabolites.

Synthesis

4,5-Dibromo-1,2-benzenediol is obtained by reacting catechol with Bromine in CCl4. Experimental procedure：In a 500mL three neck round bottom flask under nitrogen, equipped with a refluxcondenser, an addition funnel and a gas outlet connected to a bubbler filled with a 10%NaOH aqueous solution, was suspended catechol (136 mmol, 15.0 g, 1 eq.) in CCl4 (150mL). Bromine (272 mmol, 43.5 g, 2 eq.) diluted in CCla(20mL) was added dropwise at 0℃ over 4.5 h. The excess of bromine was neutralized with aqueous NaHSO4 (150mL,40% solution). The mixture was filtrated and the solids were dissolved in CCLa,washed with water and dried in vacuum. The obtained 4,5-dibromocatechol (30.2 g)was then recrystallized from CHCl3 (220 mL) to afford a white crystalline solid (22.5 g,62%).

InChI:InChI=1/C6H4Br2O2/c7-3-1-5(9)6(10)2-4(3)8/h1-2,9-10H

Upstream product

• 67-66-3 chloroform 
• 7726-95-6 bromine 
• 120-80-9 benzene-1,2-diol 
• 7664-93-9 sulfuric acid 
• 14005-14-2 2,2-dimethyl-1,3-benzodioxole 
• 37895-73-1 1,2-dibromo-4,5-dimethoxybenzene 
• 64-19-7 acetic acid 
• 114414-23-2 5,6-dibromo-2,2-dimethyl-benzo[1,3]dioxole 

Downstream Products

• 113684-82-5 1,2-dibromo-4,5-di-n-butoxybenzene 
• 118132-02-8 1,2-Dibromo-4,5-diethoxy-benzene 
• 130996-04-2 1,2-Dibromo-4,5-bis(pentyloxy)benzene 
• 118132-03-9 1,2-dibromo-4,5-bis(hexyloxy)benzene 
• 118132-04-0 1,2-Dibromo-4,5-bis(octyloxy)benzene 
• 114364-55-5 1,2-dibromo-4',5'-di-n-dodecyloxybenzene 
• 118464-38-3 1,2-dibromo-4,5-dipropyloxybenzene 
• 5279-32-3 5,6-dibromo-1,3-benzodioxole 
• 41757-99-7 1,2-bis[2-(2-hydroxyethoxy)ethoxy]benzene 
• 161807-05-2 1,2-bis<2'-(2''-hydroxyethoxy)ethoxy>-4,5-dibromobenzene 
• 1243655-69-7 1,2-dibromo-4,5-bis[2'-(2-benzyloxyethoxy)ethoxy]benzene 
• 854660-79-0 1,2-dibromo-4,5-dimethoxy-3-nitrobenzene 
• 126190-05-4 S-(2,3-Dibromo-5,6-dihydroxyphenyl)mercapturic acid 
• 130996-05-3 1,2-Dicyano-4,5-bis(pentyloxy)benzene 

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