(S)-N-[(4-methoxylphenyl)-2-methoxylphenylmethyl]-4-nitrobenzenesulfonamide

Base Information

• Chemical Name: (S)-N-[(4-methoxylphenyl)-2-methoxylphenylmethyl]-4-nitrobenzenesulfonamide
• CAS No.: 1258545-51-5
• Molecular Formula: C₂₁H₂₀N₂O₆S
• Molecular Weight: 428.466
• Mol file: 1258545-51-5.mol

Synonyms:(S)-N-[(4-methoxylphenyl)-2-methoxylphenylmethyl]-4-nitrobenzenesulfonamide

Chemical Property of (S)-N-[(4-methoxylphenyl)-2-methoxylphenylmethyl]-4-nitrobenzenesulfonamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of (S)-N-[(4-methoxylphenyl)-2-methoxylphenylmethyl]-4-nitrobenzenesulfonamide

There total 2 articles about (S)-N-[(4-methoxylphenyl)-2-methoxylphenylmethyl]-4-nitrobenzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

N-(2-methoxybenzylidene)-4-nitrobenzenesulfonamide (1202919-74-1) + 2,4,6-tris(4-methoxyphenyl)boroxine (7294-51-1) → (S)-N-[(4-methoxylphenyl)-2-methoxylphenylmethyl]-4-nitrobenzenesulfonamide (1258545-51-5)

Guidance literature:

With [{(M,S_S,S_S)-p-Tol-binaso}Rh(OH)]2; In water; toluene; at 25 ℃; for 14h; enantioselective reaction; Glovebox; Sealed tube; Inert atmosphere;

DOI:10.1002/adsc.201500975

Reference yield: 96.0%

N-(2-methoxybenzylidene)-4-nitrobenzenesulfonamide (1202919-74-1) + 4-methoxyphenylboronic acid (5720-07-0) → (S)-N-[(4-methoxylphenyl)-2-methoxylphenylmethyl]-4-nitrobenzenesulfonamide (1258545-51-5)

Guidance literature:

4-methoxyphenylboronic acid; With (3aS,6aS)-3,6-diphenyl-1,3a,4,6a-tetrahydropentalene; chlorobis(ethylene)rhodium(I) dimer; In toluene; at 40 ℃; for 0.5h; Inert atmosphere;

N-(2-methoxybenzylidene)-4-nitrobenzenesulfonamide; With potassium hydrogen bifluoride; In water; toluene; at 40 ℃; optical yield given as %ee; enantioselective reaction; Inert atmosphere;

DOI:10.1055/s-0030-1258210

upstream raw materials:

N-(2-methoxybenzylidene)-4-nitrobenzenesulfonamide

4-methoxyphenylboronic acid

2,4,6-tris(4-methoxyphenyl)boroxine