3-[(pentafluorophenyl)(pentafluorophenylamino)methyl]but-3-en-2-one

Base Information

• Chemical Name: 3-[(pentafluorophenyl)(pentafluorophenylamino)methyl]but-3-en-2-one
• CAS No.: 851867-22-6
• Molecular Formula: C₁₇H₇F₁₀NO
• Molecular Weight: 431.233
• Mol file: 851867-22-6.mol

Synonyms:3-[(pentafluorophenyl)(pentafluorophenylamino)methyl]but-3-en-2-one

Chemical Property of 3-[(pentafluorophenyl)(pentafluorophenylamino)methyl]but-3-en-2-one

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of 3-[(pentafluorophenyl)(pentafluorophenylamino)methyl]but-3-en-2-one

There total 1 articles about 3-[(pentafluorophenyl)(pentafluorophenylamino)methyl]but-3-en-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

N-pentafluorophenyl-pentafluorophenylaldimine (853-75-8) + methyl vinyl ketone (78-94-4,25038-87-3) → 3-[(pentafluorophenyl)(pentafluorophenylamino)methyl]but-3-en-2-one (851867-22-6) + 3-methylidene-5-[(pentafluorophenyl)(pentafluorophenylamino)methyl]heptane-2,6-dione

Guidance literature:

With triphenylphosphine; In tetrahydrofuran; at 20 ℃; for 12h;

DOI:10.1016/j.tet.2005.01.130

Reference yield:

3-[(pentafluorophenyl)(pentafluorophenylamino)methyl]but-3-en-2-one (851867-22-6) + methyl vinyl ketone (78-94-4,25038-87-3) → 3-methylidene-5-[(pentafluorophenyl)(pentafluorophenylamino)methyl]heptane-2,6-dione + 3-methyleneheptane-2,6-dione (22289-05-0)

Guidance literature:

With 1,4-diaza-bicyclo[2.2.2]octane; In N,N-dimethyl-formamide; at 20 ℃;

DOI:10.1016/j.tet.2005.01.130

Reference yield:

3-[(pentafluorophenyl)(pentafluorophenylamino)methyl]but-3-en-2-one (851867-22-6) → 3-methyl-4-methylidene-6-[(pentafluorophenyl)(pentafluorophenylamino)methyl]cyclohex-2-en-1-one

Guidance literature:

Multi-step reaction with 2 steps

1: 1,4-diazabicyclo[2.2.2]octane / dimethylformamide / 20 °C

2: 60 percent / K₂CO₃ / ethanol / 4 h / 20 °C

With 1,4-diaza-bicyclo[2.2.2]octane; potassium carbonate; In ethanol; N,N-dimethyl-formamide;

DOI:10.1016/j.tet.2005.01.130

upstream raw materials:

N-pentafluorophenyl-pentafluorophenylaldimine

methyl vinyl ketone

Downstream raw materials:

3-methyleneheptane-2,6-dione