(2R,3S,5S,6R)-2,6-diazido-7-(trityloxy)heptane-1,3,5-triol

Base Information

• Chemical Name: (2R,3S,5S,6R)-2,6-diazido-7-(trityloxy)heptane-1,3,5-triol
• CAS No.: 1190632-07-5
• Molecular Formula: C₂₆H₂₈N₆O₄
• Molecular Weight: 488.546
• Mol file: 1190632-07-5.mol

Synonyms:(2R,3S,5S,6R)-2,6-diazido-7-(trityloxy)heptane-1,3,5-triol

Chemical Property of (2R,3S,5S,6R)-2,6-diazido-7-(trityloxy)heptane-1,3,5-triol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2R,3S,5S,6R)-2,6-diazido-7-(trityloxy)heptane-1,3,5-triol

There total 2 articles about (2R,3S,5S,6R)-2,6-diazido-7-(trityloxy)heptane-1,3,5-triol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

(2R,3S,5S,6R)-2,6-diazidoheptane-1,3,5,7-tetraol (1190632-06-4) + trityl chloride (76-83-5) → (2R,3S,5S,6R)-2,6-diazido-7-(trityloxy)heptane-1,3,5-triol (1190632-07-5) + C45H42N6O4 (1190632-08-6)

Guidance literature:

With pyridine; at 60 ℃; for 5h; Inert atmosphere;

DOI:10.1021/jo901007v

Reference yield: 48.0%

C45H42N6O4 (1190632-08-6) → (2R,3S,5S,6R)-2,6-diazidoheptane-1,3,5,7-tetraol (1190632-06-4) + (2R,3S,5S,6R)-2,6-diazido-7-(trityloxy)heptane-1,3,5-triol (1190632-07-5)

Guidance literature:

With trifluoroacetic acid; In methanol; at 20 ℃; for 10h; pH=2; Inert atmosphere;

DOI:10.1021/jo901007v

Reference yield: 73.0%

2-Methoxypropene (116-11-0) + (2R,3S,5S,6R)-2,6-diazido-7-(trityloxy)heptane-1,3,5-triol (1190632-07-5) → C29H32N6O4 (1190632-10-0) + (2S,3R)-3-azido-1-((4S,5R)-5-azido-2,2-dimethyl-1,3-dioxan-4-yl)-4-(trityloxy)butan-2-ol (1190632-09-7)

Guidance literature:

With pyridinium p-toluenesulfonate; In N,N-dimethyl-formamide; at 50 ℃; for 4h; Inert atmosphere;

DOI:10.1021/jo901007v

upstream raw materials:

(2R,3S,5S,6R)-2,6-diazidoheptane-1,3,5,7-tetraol

trityl chloride

C₄₅H₄₂N₆O₄

Downstream raw materials:

C₂₉H₃₂N₆O₄

(2S,3R)-3-azido-1-((4S,5R)-5-azido-2,2-dimethyl-1,3-dioxan-4-yl)-4-(trityloxy)butan-2-ol

C₃₃H₄₀N₆O₅