imidazo[1,2-a]pyridine-6-carboxylic acid 4-(4-pyrrolidin-1-ylpiperidine-1-sulfonyl)benzylamide

Base Information

Chemical Name:imidazo[1,2-a]pyridine-6-carboxylic acid 4-(4-pyrrolidin-1-ylpiperidine-1-sulfonyl)benzylamide
CAS No.:1453174-57-6
Molecular Formula:C₂₄H₂₉N₅O₃S
Molecular Weight:467.592
Hs Code.:

Synonyms:imidazo[1,2-a]pyridine-6-carboxylic acid 4-(4-pyrrolidin-1-ylpiperidine-1-sulfonyl)benzylamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of imidazo[1,2-a]pyridine-6-carboxylic acid 4-(4-pyrrolidin-1-ylpiperidine-1-sulfonyl)benzylamide

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Technology Process of imidazo[1,2-a]pyridine-6-carboxylic acid 4-(4-pyrrolidin-1-ylpiperidine-1-sulfonyl)benzylamide

There total 4 articles about imidazo[1,2-a]pyridine-6-carboxylic acid 4-(4-pyrrolidin-1-ylpiperidine-1-sulfonyl)benzylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1453176-75-4
4-{[(imidazo[1,2-a]pyridine-6-carbonyl)-amino]-methyl}-benzenesulfonyl chloride

: 172281-91-3,4983-39-5
4-(pyrrolidin-1-yl)piperidine hydrochloride

: 1453174-57-6
imidazo[1,2-a]pyridine-6-carboxylic acid 4-(4-pyrrolidin-1-ylpiperidine-1-sulfonyl)benzylamide

Guidance literature:: With triethylamine; In dichloromethane; at 20 ℃; for 24h;

Reference yield:

: 139022-25-6
imidazo[1,2-a]pyridine-6-carboxylic acid

: 1453174-57-6
imidazo[1,2-a]pyridine-6-carboxylic acid 4-(4-pyrrolidin-1-ylpiperidine-1-sulfonyl)benzylamide

Guidance literature:: Multi-step reaction with 3 steps

1: triethylamine; benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate / dichloromethane / 24 h / 20 °C

2: chlorosulfonic acid / 2 h / 20 °C / Cooling with ice

3: triethylamine / dichloromethane / 24 h / 20 °C

With chlorosulfonic acid; benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; triethylamine; In dichloromethane;

Reference yield:

: 100-46-9
benzylamine

: 1453174-57-6
imidazo[1,2-a]pyridine-6-carboxylic acid 4-(4-pyrrolidin-1-ylpiperidine-1-sulfonyl)benzylamide

Guidance literature:: Multi-step reaction with 3 steps

1: triethylamine; benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate / dichloromethane / 24 h / 20 °C

2: chlorosulfonic acid / 2 h / 20 °C / Cooling with ice

3: triethylamine / dichloromethane / 24 h / 20 °C

With chlorosulfonic acid; benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; triethylamine; In dichloromethane;