4-Hydroximino-1-phenyl-1,2,3,4-tetrahydro-1-naphthylessigsaeureethylester

Base Information

• Chemical Name: 4-Hydroximino-1-phenyl-1,2,3,4-tetrahydro-1-naphthylessigsaeureethylester
• CAS No.: 3389-90-0
• Molecular Formula: C₂₀H₂₁NO₃
• Molecular Weight: 323.392
• Mol file: 3389-90-0.mol

Synonyms:4-Hydroximino-1-phenyl-1,2,3,4-tetrahydro-1-naphthylessigsaeureethylester

Chemical Property of 4-Hydroximino-1-phenyl-1,2,3,4-tetrahydro-1-naphthylessigsaeureethylester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-Hydroximino-1-phenyl-1,2,3,4-tetrahydro-1-naphthylessigsaeureethylester

There total 3 articles about 4-Hydroximino-1-phenyl-1,2,3,4-tetrahydro-1-naphthylessigsaeureethylester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

4-Oxo-1-phenyl-1,2,3,4-tetrahydro-1-naphthylessigsaeureethylester (3389-88-6) → 4-Hydroximino-1-phenyl-1,2,3,4-tetrahydro-1-naphthylessigsaeureethylester (3389-90-0)

Guidance literature:

With hydroxylamine hydrochloride; sodium acetate; In ethanol; for 2h; Heating;

DOI:10.1002/ardp.19823150109

Reference yield:

4-Phenyl-4-(carboxy-methyl)-1-tetralon (81124-87-0) → 4-Hydroximino-1-phenyl-1,2,3,4-tetrahydro-1-naphthylessigsaeureethylester (3389-90-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 78 percent / p-toluenesulfonic acid / CHCl₃ / 8 h

2: 93 percent / H₂NOH*HCl, CH₃COONa / aq. ethanol / 2 h / Heating

With hydroxylamine hydrochloride; sodium acetate; toluene-4-sulfonic acid; In ethanol; chloroform;

DOI:10.1002/ardp.19823150109

Reference yield:

→ 4-Hydroximino-1-phenyl-1,2,3,4-tetrahydro-1-naphthylessigsaeureethylester (3389-90-0)

Guidance literature:

entspr. Ketoaethylester, NH2OH, in sd. NaOH;

upstream raw materials:

4-Oxo-1-phenyl-1,2,3,4-tetrahydro-1-naphthylessigsaeureethylester

4-Phenyl-4-(carboxy-methyl)-1-tetralon

Downstream raw materials:

4-Amino-1-phenyl-1,2,3,4-tetrahydro-1-naphthylessigsaeureethylester

5-Phenyl-6,7-benzo-2-azabicyclo<3,2,2>nonen-3-on

2-Methyl-5-phenyl-6,7-benzo-2-azabicyclo<3,2,2>nonen-3-on

4-Trifluoracetylamino-1-phenyl-1,2,3,4-tetrahydro-1-naphthylessigsaeureethylester