Technology Process of N-ethyl-N-(2-phenoxyethyl)cyclohexylamine
There total 3 articles about N-ethyl-N-(2-phenoxyethyl)cyclohexylamine which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
N-cyclohexyl-N-(2-phenoxyethyl)acetamide;
With
lithium aluminium tetrahydride;
In
tetrahydrofuran;
at 20 ℃;
for 12h;
Cooling with ice;
With
water; sodium hydroxide;
In
tetrahydrofuran;
at 20 ℃;
Cooling with ice;
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: sodium hydroxide / water / 5 h / Reflux
2.1: potassium carbonate; sodium iodide / ethanol / 12 h / Reflux
3.1: triethylamine / dichloromethane / 2 h / -30 °C
4.1: lithium aluminium tetrahydride / tetrahydrofuran / 12 h / 20 °C / Cooling with ice
4.2: 20 °C / Cooling with ice
With
lithium aluminium tetrahydride; potassium carbonate; triethylamine; sodium iodide; sodium hydroxide;
In
tetrahydrofuran; ethanol; dichloromethane; water;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: potassium carbonate; sodium iodide / ethanol / 12 h / Reflux
2.1: triethylamine / dichloromethane / 2 h / -30 °C
3.1: lithium aluminium tetrahydride / tetrahydrofuran / 12 h / 20 °C / Cooling with ice
3.2: 20 °C / Cooling with ice
With
lithium aluminium tetrahydride; potassium carbonate; triethylamine; sodium iodide;
In
tetrahydrofuran; ethanol; dichloromethane;
