ethyl {4-[{[2-amino-4-(morpholin-4-yl)-1,3,5-triazin-6-yl]methyl}amino]benzoyl}-L-glutamate

Base Information

Chemical Name:ethyl {4-[{[2-amino-4-(morpholin-4-yl)-1,3,5-triazin-6-yl]methyl}amino]benzoyl}-L-glutamate
CAS No.:871332-26-2
Molecular Formula:C₂₂H₂₉N₇O₆
Molecular Weight:487.516
Hs Code.:

Synonyms:ethyl {4-[{[2-amino-4-(morpholin-4-yl)-1,3,5-triazin-6-yl]methyl}amino]benzoyl}-L-glutamate

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Chemical Property of ethyl {4-[{[2-amino-4-(morpholin-4-yl)-1,3,5-triazin-6-yl]methyl}amino]benzoyl}-L-glutamate

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Technology Process of ethyl {4-[{[2-amino-4-(morpholin-4-yl)-1,3,5-triazin-6-yl]methyl}amino]benzoyl}-L-glutamate

There total 3 articles about ethyl {4-[{[2-amino-4-(morpholin-4-yl)-1,3,5-triazin-6-yl]methyl}amino]benzoyl}-L-glutamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 38.0%

: 64942-50-3
2-amino-pentanedioic acid 1-ethyl ester; hydrochloride

: 871332-18-2
4-({[2-amino-4-(morpholin-4-yl)-1,3,5-triazin-6-yl]methyl}amino)benzoic acid

: 871332-26-2
ethyl {4-[{[2-amino-4-(morpholin-4-yl)-1,3,5-triazin-6-yl]methyl}amino]benzoyl}-L-glutamate

Guidance literature:: With diethyl cyanophosphonate; triethylamine; In N,N-dimethyl-formamide; at 20 ℃; for 12h;

Reference yield:

: 871332-14-8
2-amino-4-(morpholin-4-yl)-6-(1-bromomethyl)-1,3,5-triazine

: 871332-26-2
ethyl {4-[{[2-amino-4-(morpholin-4-yl)-1,3,5-triazin-6-yl]methyl}amino]benzoyl}-L-glutamate

Guidance literature:: Multi-step reaction with 2 steps

1: 80 percent / dimethylformamide / 12 h / 20 °C

2: 38 percent / diethyl cyanophosphonate; triethylamine / dimethylformamide / 12 h / 20 °C

With diethyl cyanophosphonate; triethylamine; In N,N-dimethyl-formamide;

Reference yield:

: 3731-59-7
moroxydine

: 871332-26-2
ethyl {4-[{[2-amino-4-(morpholin-4-yl)-1,3,5-triazin-6-yl]methyl}amino]benzoyl}-L-glutamate

Guidance literature:: Multi-step reaction with 3 steps

1: 39 percent / methanol / 2.5 h / 20 °C

2: 80 percent / dimethylformamide / 12 h / 20 °C

3: 38 percent / diethyl cyanophosphonate; triethylamine / dimethylformamide / 12 h / 20 °C

With diethyl cyanophosphonate; triethylamine; In methanol; N,N-dimethyl-formamide;