N-[(E)-(3S,4S,5R)-3,4,5-Tris-benzyloxy-6,6-bis-ethylsulfanyl-1-(toluene-4-sulfonyl)-hex-1-enyl]-formamide

Base Information

• Chemical Name: N-[(E)-(3S,4S,5R)-3,4,5-Tris-benzyloxy-6,6-bis-ethylsulfanyl-1-(toluene-4-sulfonyl)-hex-1-enyl]-formamide
• CAS No.: 212691-32-2
• Molecular Formula: C₃₉H₄₅NO₆S₃
• Molecular Weight: 719.987

Synonyms:N-[(E)-(3S,4S,5R)-3,4,5-Tris-benzyloxy-6,6-bis-ethylsulfanyl-1-(toluene-4-sulfonyl)-hex-1-enyl]-formamide

Chemical Property of N-[(E)-(3S,4S,5R)-3,4,5-Tris-benzyloxy-6,6-bis-ethylsulfanyl-1-(toluene-4-sulfonyl)-hex-1-enyl]-formamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-[(E)-(3S,4S,5R)-3,4,5-Tris-benzyloxy-6,6-bis-ethylsulfanyl-1-(toluene-4-sulfonyl)-hex-1-enyl]-formamide

There total 2 articles about N-[(E)-(3S,4S,5R)-3,4,5-Tris-benzyloxy-6,6-bis-ethylsulfanyl-1-(toluene-4-sulfonyl)-hex-1-enyl]-formamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

1-isocyanatomethanesulfonyl-4-methyl-benzene (10564-55-3) + (2R,3S,4R)-2,3,4-Tris-benzyloxy-5,5-bis-ethylsulfanyl-pentanal (212691-31-1) → N-[(E)-(3S,4S,5R)-3,4,5-Tris-benzyloxy-6,6-bis-ethylsulfanyl-1-(toluene-4-sulfonyl)-hex-1-enyl]-formamide (212691-32-2)

Guidance literature:

With potassium tert-butylate; In 1,2-dimethoxyethane; at -30 ℃; for 1.5h;

DOI:10.1016/S0040-4020(98)00561-4

Reference yield:

2,3,4-tri-O-benzyl-D-galactose diethyldithioacetal (212691-30-0) → N-[(E)-(3S,4S,5R)-3,4,5-Tris-benzyloxy-6,6-bis-ethylsulfanyl-1-(toluene-4-sulfonyl)-hex-1-enyl]-formamide (212691-32-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 56 percent / NaIO₄ / acetone; H₂O / Ambient temperature

2: 97 percent / t-BuOK / 1,2-dimethoxy-ethane / 1.5 h / -30 °C

With sodium periodate; potassium tert-butylate; In 1,2-dimethoxyethane; water; acetone;

DOI:10.1016/S0040-4020(98)00561-4

Reference yield: 95.0%

N-[(E)-(3S,4S,5R)-3,4,5-Tris-benzyloxy-6,6-bis-ethylsulfanyl-1-(toluene-4-sulfonyl)-hex-1-enyl]-formamide (212691-32-2) → Methylene-[(E)-(3S,4S,5R)-3,4,5-tris-benzyloxy-6,6-bis-ethylsulfanyl-1-(toluene-4-sulfonyl)-hex-1-enyl]-amine

Guidance literature:

With triethylamine; trichlorophosphate; In 1,2-dimethoxyethane; at -5 ℃; for 1.5h;

DOI:10.1016/S0040-4020(98)00561-4

upstream raw materials:

1-isocyanatomethanesulfonyl-4-methyl-benzene

(2R,3S,4R)-2,3,4-Tris-benzyloxy-5,5-bis-ethylsulfanyl-pentanal

2,3,4-tri-O-benzyl-D-galactose diethyldithioacetal

Downstream raw materials:

(6S,7R,8S)-6,7,8-Tris-benzyloxy-5,6,7,8-tetrahydro-imidazo[1,5-a]pyridine

(2S,3S,4S)-2,3,4-Tris-benzyloxy-4-(3H-imidazol-4-yl)-butan-1-ol

(6R,7S,8S)-6,7,8-Tris-benzyloxy-5,6,7,8-tetrahydro-imidazo[1,5-a]pyridin-5-ol

5-((1S,2S,3R)-1,2,3-Tris-benzyloxy-4,4-bis-ethylsulfanyl-butyl)-1H-imidazole

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 212691-32-2 N-[(E)-(3S,4S,5R)-3,4,5-Tris-benzyloxy-6,6-bis-ethylsulfanyl-1-(toluene-4-sulfonyl)-hex-1-enyl]-formamide

Send

Send

Metric Ton KG G Pound L ML

Send

Send