(3R)-3-amino-4-methylpentanoic acid

Base Information

Chemical Name:(3R)-3-amino-4-methylpentanoic acid
CAS No.:75992-50-6
Molecular Formula:C₆H₁₃NO₂
Molecular Weight:131.175
Hs Code.:2922499990
European Community (EC) Number:674-817-1
DSSTox Substance ID:DTXSID20375828
Nikkaji Number:J353.113I
Wikidata:Q27098137
Metabolomics Workbench ID:50181
Mol file:75992-50-6.mol

Synonyms:(r)-3-amino-4-methylpentanoic acid;75992-50-6;(3R)-3-amino-4-methylpentanoic acid;(3R)-beta-Leucine;(r)-beta-homovaline;(r)-homo-beta-valine;(r)-3-amino-4-methyl-pentanoic acid;L-beta-Leucine;Pentanoic acid, 3-amino-4-methyl-, (3R)-;(3R)-3-Amino-4-methylvaleric acid;L-beta-homovaline;(3R)-beta-2-Amino-4-methylvaleric acid;MFCD01076231;beta-3-homovaline;(R)-b-homovaline;(R)- -Homovaline;(3R)--leucine;C02486;SCHEMBL289124;CHEBI:15604;DTXSID20375828;GLUJNGJDHCTUJY-RXMQYKEDSA-N;(R)-3-Amino-4-methylpentanoicacid;AMY14234;AKOS006282077;DS-13474;CS-0039103;EN300-207852;(R)-3-amino-4-methyl-pentanoic acid, AldrichCPR;A848699;Q27098137

Suppliers and Price of (3R)-3-amino-4-methylpentanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(R)-3-Amino-4-methylpentanoicacid
500mg
$ 330.00

SynQuest Laboratories
(R)-3-Amino-4-methylpentanoic acid 97%
1 g
$ 240.00

SynQuest Laboratories
(R)-3-Amino-4-methylpentanoic acid 97%
5 g
$ 920.00

Crysdot
(R)-3-Amino-4-methylpentanoicacid 95+%
5g
$ 457.00

Chemenu
(R)-3-Amino-4-methylpentanoicacid 95%
5g
$ 432.00

AstaTech
(R)-HOMO-BETA-VALINE 97%
25 / G
$ 1400.00

AstaTech
(R)-HOMO-BETA-VALINE 97%
5 / G
$ 460.00

AstaTech
(R)-HOMO-BETA-VALINE 97%
1 / G
$ 110.00

American Custom Chemicals Corporation
(R)-3-AMINO-4-METHYL-PENTANOIC ACID 95.00%
1G
$ 721.59

Ambeed
(R)-3-Amino-4-methylpentanoicacid 95%
250mg
$ 56.00

Total 32 raw suppliers

Chemical Property of (3R)-3-amino-4-methylpentanoic acid

Chemical Property:

Vapor Pressure:0.0212mmHg at 25°C
Melting Point:206℃
Refractive Index:1.462
Boiling Point:232°C at 760 mmHg
PKA:3.81±0.10(Predicted)
Flash Point:94.1°C
PSA：63.32000
Density:1.035g/cm³
LogP:1.14470
Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C
XLogP3:-2.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:131.094628657
Heavy Atom Count:9
Complexity:101

Purity/Quality:

97% ^*data from raw suppliers

(R)-3-Amino-4-methylpentanoicacid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)C(CC(=O)O)N
Isomeric SMILES:CC(C)[C@@H](CC(=O)O)N

Technology Process of (3R)-3-amino-4-methylpentanoic acid

There total 16 articles about (3R)-3-amino-4-methylpentanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: (R)-3-((S)-2-Methoxymethyl-pyrrolidin-1-ylamino)-4-methyl-pentanoic acid tert-butyl ester

: 5699-54-7,37631-91-7,40469-85-0,75992-50-6
(R)-3-amino-4-methylpentanoic acid

Guidance literature:: With hydrogen; nickel; In water; under 7.5 - 9.5 Torr; Heating;

Reference yield: 46.0%

: N-PhAc-β-leucine

: (3S)-4-methyl-3-phenylacetamidopentanoic acid

: 5699-54-7,37631-91-7,40469-85-0,75992-50-6
(R)-3-amino-4-methylpentanoic acid

Guidance literature:: With sodium hydroxide; water; In isopropyl alcohol; at 28 ℃; for 24h; pH=8; Resolution of racemate; Enzymatic reaction;

Reference yield:

: N-PhAc-β-leucine

: 5699-54-7,37631-91-7,40469-85-0,75992-50-6
(R)-3-amino-4-methylpentanoic acid

Guidance literature:: With penicillin G acylase from Achromobacter sp. CCM 4824; water; at 30 ℃; pH=7; Reagent/catalyst; enantioselective reaction; Enzymatic reaction;
DOI:10.1016/j.molcatb.2015.09.008