2-(3-fluoro-4-methoxycarbonylphenyl)-4,4,6-trimethyl-1,3,2-dioxaborinane

Base Information

• Chemical Name: 2-(3-fluoro-4-methoxycarbonylphenyl)-4,4,6-trimethyl-1,3,2-dioxaborinane
• CAS No.: 1214273-29-6
• Molecular Formula: C₁₄H₁₈BFO₄
• Molecular Weight: 280.104
• Mol file: 1214273-29-6.mol

Synonyms:2-(3-fluoro-4-methoxycarbonylphenyl)-4,4,6-trimethyl-1,3,2-dioxaborinane

Chemical Property of 2-(3-fluoro-4-methoxycarbonylphenyl)-4,4,6-trimethyl-1,3,2-dioxaborinane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(3-fluoro-4-methoxycarbonylphenyl)-4,4,6-trimethyl-1,3,2-dioxaborinane

There total 1 articles about 2-(3-fluoro-4-methoxycarbonylphenyl)-4,4,6-trimethyl-1,3,2-dioxaborinane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

4,4,6-trimethyl-1,3,2-dioxaborinane (10199-14-1,23894-82-8) + 4-chloro-2-fluorobenzoic acid methyl ester (148893-72-5) → methyl 2-fluorobenzoate (394-35-4) + 2-(3-fluoro-4-methoxycarbonylphenyl)-4,4,6-trimethyl-1,3,2-dioxaborinane (1214273-29-6)

Guidance literature:

With 1,3-bis[(diphenylphosphino)propane]dichloronickel(II); tetrabutylammomium bromide; triethylamine; In 1,4-dioxane; at 100 ℃; for 24h;

DOI:10.3987/COM-09-S(S)63

Reference yield: 45.0%

2-(3-fluoro-4-methoxycarbonylphenyl)-4,4,6-trimethyl-1,3,2-dioxaborinane (1214273-29-6) + toluene (108-88-3,15644-74-3,16713-13-6) → 3-fluoro-4-methoxycarbonyldiphenylmethane

Guidance literature:

With 1,10-Phenanthroline; copper(I) iodide dimethyl sulfide complex; di-tert-butyl peroxide; at 90 ℃; for 48h; Inert atmosphere; Glovebox; Sealed tube;

DOI:10.1021/jacs.7b03387

upstream raw materials:

4,4,6-trimethyl-1,3,2-dioxaborinane

4-chloro-2-fluorobenzoic acid methyl ester