148893-72-5

Basic information

• Product Name: Methyl4-chloro-2-fluoroBenzoate
• Synonyms: 2-fluoro-4-Chlorobenzoic acid methyl ester
• CAS NO: 148893-72-5
• Molecular Formula: C8H6ClFO2
• Molecular Weight: 188.58
• Product Categories: blocks;Carboxes
• Mol File: 148893-72-5.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 228.4 °C at 760 mmHg
• Flash Point: 96.1 °C
• Appearance: /
• Density: 1.314 g/cm³
• Vapor Pressure: 0.0736mmHg at 25°C
• Refractive Index: 1.51
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: Methyl4-chloro-2-fluoroBenzoate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl4-chloro-2-fluoroBenzoate(148893-72-5)
• EPA Substance Registry System: Methyl4-chloro-2-fluoroBenzoate(148893-72-5)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 148893-72-5(Hazardous Substances Data)

Usage

General Description

Methyl 4-chloro-2-fluoro benzoate is an organic compound that consists of a methyl group, a 4-chloro-2-fluoro benzoyl group, and an ester functional group. It is commonly used as an intermediate for the synthesis of pharmaceuticals and agrochemicals. The 4-chloro-2-fluoro substitution pattern on the benzene ring imparts specific physical and chemical properties to the compound, making it useful for various applications. This chemical may have different uses in different industries, such as in the production of insecticides or as a building block for drug development. It is important to handle and use this compound with care, following proper safety protocols and regulations.

InChI:InChI=1/C8H6ClFO2/c1-12-8(11)6-3-2-5(9)4-7(6)10/h2-4H,1H3

Upstream product

• 67-56-1 methanol 
• 446-30-0 4-chloro-2-fluorobenzoic acid 
• 74-88-4 methyl iodide 
• 201230-82-2 carbon monoxide 
• 348-59-4 1,4-dichloro-2-fluorobenzene 
• 42087-80-9 methyl 4-chloro-2-nitrobenzoate 

Downstream Products

• 175596-01-7 methyl 4-cyano-2-fluorobenzoate 
• 37135-28-7 4-ethyl-2-fluorobenzoic acid 
• 267880-83-1 3-(4-chloro-2-fluorophenyl)-3-oxopropanenitrile 

Relevant articles and documents

Preparation method of benzothiazepine oxide, product prepared by preparation method and application of product

The invention discloses a preparation method of a benzothiazepine oxide, a product prepared by the preparation method and application of the product, and relates to the technical field of chemical synthesis. The method comprises the following steps: takin

Chemoselectivity of cobalt-catalysed carbonylation-A reliable platform for the synthesis of fluorinated benzoic acids

The cobalt-catalysed methoxycarbonylation of polysubstituted bromo,fluoro- and chloro,fluorobenzenes and 1,2,4-trichlorobenzene with emphasis on the chemo- and regio-selectivity of the reaction is described. The structures of isolated products of 1,4-dichloro-2-fluorobenzene carbonylation were determined by single-crystal X-ray diffraction. The fact that the fluorine substituents in the studied compounds remain intact indicates in favor of the anion-radical activation of aryl halides by a cobalt catalyst. For the first time, a universal method of preparation of the various fluorobenzoic acid derivatives from available raw materials with a good yield has been elaborated.