3,5a,9-Trimethyl-3a,5,5a,9,9a,9b-hexahydronaphtho[1,2-b]furan-2,8(3h,4h)-dione

Base Information

Chemical Name:3,5a,9-Trimethyl-3a,5,5a,9,9a,9b-hexahydronaphtho[1,2-b]furan-2,8(3h,4h)-dione
CAS No.:39813-41-7
Molecular Formula:C₁₅H₂₀O₃
Molecular Weight:248.322
Hs Code.:
NSC Number:138611,250831,240832
DSSTox Substance ID:DTXSID00300739
Wikidata:Q82044045

Synonyms:39813-41-7;3,5a,9-trimethyl-3a,5,5a,9,9a,9b-hexahydronaphtho[1,2-b]furan-2,8(3h,4h)-dione;NSC240832;DTXSID00300739;NSC138611;NSC250831;NSC-138611;NSC-240832;NSC-250831;(3.ALPHA.,5A.BETA.,9.BETA.,9A.BETA.,9B.BETA.)-OCTAHYDRO-3,5A,9-TRIMETHYLNAPHTHO[1,2-B]FURAN-2,8(3H,4H)-DIONE

Suppliers and Price of 3,5a,9-Trimethyl-3a,5,5a,9,9a,9b-hexahydronaphtho[1,2-b]furan-2,8(3h,4h)-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3,5a,9-Trimethyl-3a,5,5a,9,9a,9b-hexahydronaphtho[1,2-b]furan-2,8(3h,4h)-dione

Chemical Property:

Vapor Pressure:8.28E-07mmHg at 25°C
XLogP3:2.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:248.14124450
Heavy Atom Count:18
Complexity:439

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1C2CCC3(C=CC(=O)C(C3C2OC1=O)C)C

Technology Process of 3,5a,9-Trimethyl-3a,5,5a,9,9a,9b-hexahydronaphtho[1,2-b]furan-2,8(3h,4h)-dione

There total 1 articles about 3,5a,9-Trimethyl-3a,5,5a,9,9a,9b-hexahydronaphtho[1,2-b]furan-2,8(3h,4h)-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 108-75-8
2,4,6-trimethyl-pyridine

: (11S)-2ξ,4-dibromo-6α-hydroxy-3-oxo-4ξH-eudesman-12-oic acid-lactone

: 39813-41-7
(3S,3aS,5aS,9S,9aR,9bS)-3,5a,9-trimethyl-3a,5,5a,9,9a,9b-hexahydro-3H,4H-naphtho[1,2-b]furan-2,8-dione

: 481-06-1
santonin

Guidance literature:: bei Siedetemperatur;
DOI:10.1021/jo01125a021

Reference yield:

: 39813-41-7
(3S,3aS,5aS,9S,9aR,9bS)-3,5a,9-trimethyl-3a,5,5a,9,9a,9b-hexahydro-3H,4H-naphtho[1,2-b]furan-2,8-dione

: 481-06-1
santonin

Guidance literature:: Multi-step reaction with 3 steps

1: Et₃N / CH₂Cl₂ / 3 h / 0 °C

2: 67.9 mg / phenyltrimethylammonium tribromide / CH₂Cl₂ / 0.25 h / 0 °C

3: 6 percent / TBAF / tetrahydrofuran / 25.5 h / 20 °C

With tetrabutyl ammonium fluoride; phenyltrimethylammonium tribromide; triethylamine; In tetrahydrofuran; dichloromethane;
DOI:10.1021/np0205250

Reference yield:

: 39813-41-7
(3S,3aS,5aS,9S,9aR,9bS)-3,5a,9-trimethyl-3a,5,5a,9,9a,9b-hexahydro-3H,4H-naphtho[1,2-b]furan-2,8-dione

: 57784-41-5
3β-hydroxy-11β-(phenylseleno)eudesm-1-eno-12,6α-lactone

Guidance literature:: Multi-step reaction with 2 steps

1.1: aluminum isopropoxide / isopropyl alcohol / 4 h / Heating

2.1: lithium diisopropyl amide / tetrahydrofuran; hexane / 2.25 h / -78 °C

2.2: 2.08 h / -78 - -40 °C

With aluminum isopropoxide; lithium diisopropyl amide; In tetrahydrofuran; hexane; isopropyl alcohol; 1.1: Meerwein-Ponndorf-Verley reduction;
DOI:10.1016/j.bmcl.2011.11.029