tert-Butyl N-{3-[(tert-butoxycarbonyl)amino]-2-hydroxypropyl}carbamate

Base Information

• Chemical Name: tert-Butyl N-{3-[(tert-butoxycarbonyl)amino]-2-hydroxypropyl}carbamate
• CAS No.: 98642-15-0
• Molecular Formula: C₁₃H₂₆N₂O₅
• Molecular Weight: 290.36
• Mol file: 98642-15-0.mol

Synonyms:(3-tert-butoxycarbonylamino-2-hydroxy-propyl)-carbamic acid tert-butyl ester

Chemical Property of tert-Butyl N-{3-[(tert-butoxycarbonyl)amino]-2-hydroxypropyl}carbamate

Chemical Property:

• Melting Point: 99-102°
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

98%min ^*data from raw suppliers

tert-Butyl N-{3-[(tert-butoxycarbonyl)amino]-2-hydroxypropyl}carbamate >95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of tert-Butyl N-{3-[(tert-butoxycarbonyl)amino]-2-hydroxypropyl}carbamate

There total 5 articles about tert-Butyl N-{3-[(tert-butoxycarbonyl)amino]-2-hydroxypropyl}carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

di-tert-butyl dicarbonate (24424-99-5) + 1,3-Diamino-2-hydroxypropane (616-29-5) → (3-tert-butoxycarbonylamino-2-hydroxy-propyl)-carbamic acid tert-butyl ester (98642-15-0)

Guidance literature:

With triethylamine; In methanol; at 20 - 50 ℃; for 1.33333h;

Reference yield: 100.0%

→ (3-tert-butoxycarbonylamino-2-hydroxy-propyl)-carbamic acid tert-butyl ester (98642-15-0)

Guidance literature:

Reference yield: 95.0%

tert-butyldicarbonate (34619-03-9) + 1,3-Diamino-2-hydroxypropane (616-29-5) → (3-tert-butoxycarbonylamino-2-hydroxy-propyl)-carbamic acid tert-butyl ester (98642-15-0)

Guidance literature:

In methanol; dichloromethane; for 1h;

DOI:10.1021/ac050423p

upstream raw materials:

di-tert-butyl dicarbonate

1,3-Diamino-2-hydroxypropane

tert-butyldicarbonate

Downstream raw materials:

2-(tert-butoxycarbonylamino)-1-(tert-butoxycarbonylaminomethyl)ethyl 4-formylbenzoate

1,3-di(t-butoxycarbonylamino)-2-(4-nitrophenyl-carbonyloxy)-propane

benzoic acid 2-tert-butoxycarbonylamino-1-(tert-butoxycarbonylaminomethyl)ethyl ester

[3-tert-butoxycarbonylamino-2-(5-fluoro-2-nitro-phenoxy)-propyl]-carbamic acid tert-butyl ester