4-dimethylthiocarbamoyloxygamma-oxobenzenebutanoic acid,methyl ester

Base Information

• Chemical Name: 4-dimethylthiocarbamoyloxygamma-oxobenzenebutanoic acid,methyl ester
• CAS No.: 91540-69-1
• Molecular Formula: C₁₄H₁₇NO₄S
• Molecular Weight: 295.359
• Mol file: 91540-69-1.mol

Synonyms:4-dimethylthiocarbamoyloxygamma-oxobenzenebutanoic acid,methyl ester

Chemical Property of 4-dimethylthiocarbamoyloxygamma-oxobenzenebutanoic acid,methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-dimethylthiocarbamoyloxygamma-oxobenzenebutanoic acid,methyl ester

There total 4 articles about 4-dimethylthiocarbamoyloxygamma-oxobenzenebutanoic acid,methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-hydroxymethyl-7-mercapto-4-oxo-4H-1-benzopyran (95903-73-4) + N,N-Dimethylthiocarbamoyl chloride (16420-13-6) → 4-dimethylthiocarbamoyloxygamma-oxobenzenebutanoic acid,methyl ester (91540-69-1)

Guidance literature:

With NaH; In N-methyl-acetamide;

Reference yield:

methoxybenzene (100-66-3) → 4-dimethylthiocarbamoyloxygamma-oxobenzenebutanoic acid,methyl ester (91540-69-1)

Guidance literature:

Multi-step reaction with 3 steps

1: AlCl₃ / 1,2-dichloro-ethane / 0 °C

2: HBr, HOAc / Heating

3: NaH / dimethylformamide

With aluminium trichloride; hydrogen bromide; sodium hydride; acetic acid; In 1,2-dichloro-ethane; N,N-dimethyl-formamide;

DOI:10.1021/jm00159a003

Reference yield:

4-(4-methoxy-phenyl)-4-oxo-butyric acid (3153-44-4) → 4-dimethylthiocarbamoyloxygamma-oxobenzenebutanoic acid,methyl ester (91540-69-1)

Guidance literature:

Multi-step reaction with 2 steps

1: HBr, HOAc / Heating

2: NaH / dimethylformamide

With hydrogen bromide; sodium hydride; acetic acid; In N,N-dimethyl-formamide;

DOI:10.1021/jm00159a003

upstream raw materials:

3-(4-hydroxybenzoyl)propionic acid

N,N-Dimethylthiocarbamoyl chloride

methoxybenzene

4-(4-methoxy-phenyl)-4-oxo-butyric acid

Downstream raw materials:

(4S,5R)-5-{4-[3-(4-Acetyl-3-hydroxy-2-propyl-phenoxy)-propylsulfanyl]-phenyl}-4-methyl-dihydro-furan-2-one

(4R,5R)-5-{4-[3-(4-Acetyl-3-hydroxy-2-propyl-phenoxy)-propylsulfanyl]-phenyl}-4-methyl-dihydro-furan-2-one

(4S,5R)-5-(4-Mercapto-phenyl)-4-methyl-dihydro-furan-2-one

(4R,5R)-5-(4-Mercapto-phenyl)-4-methyl-dihydro-furan-2-one