C₂₆H₂₆FN₃O₃

Base Information

Chemical Name:C₂₆H₂₆FN₃O₃
CAS No.:1333400-25-1
Molecular Formula:C₂₆H₂₆FN₃O₃
Molecular Weight:447.509
Hs Code.:

C<sub>26</sub>H<sub>26</sub>FN<sub>3</sub>O<sub>3</sub>

Synonyms:C₂₆H₂₆FN₃O₃

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Chemical Property of C₂₆H₂₆FN₃O₃

Chemical Property:

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Technology Process of C₂₆H₂₆FN₃O₃

There total 11 articles about C₂₆H₂₆FN₃O₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₃₁H₃₄FN₃O₅

: 1333400-25-1
C₂₆H₂₆FN₃O₃

Guidance literature:: In dichloromethane; at 30 ℃; for 16h; Acidic conditions;
DOI:10.1016/j.bmcl.2013.09.040

Reference yield:

: 2247-88-3
3-fluoro-pyridin-4-ylamine

: 1333400-25-1
C₂₆H₂₆FN₃O₃

Guidance literature:: Multi-step reaction with 4 steps

1.1: dmap; triethylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate / N,N-dimethyl acetamide / 16 h / 30 °C

2.1: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium carbonate / N,N-dimethyl-formamide; water / 16 h / 100 °C / Inert atmosphere

3.1: trialkylamine

3.2: 20 °C

4.1: dichloromethane / 16 h / 30 °C / Acidic conditions

With dmap; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium carbonate; triethylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; In dichloromethane; N,N-dimethyl acetamide; water; N,N-dimethyl-formamide; 2.1: |Suzuki Coupling;
DOI:10.1016/j.bmcl.2013.09.040

Reference yield:

: 1333400-88-6
[2-bromo-4-{3-fluoro-pyridin-4-ylcarbamoyl}-benzyl]-carbamic acid tert butyl ester

: 1333400-25-1
C₂₆H₂₆FN₃O₃

Guidance literature:: Multi-step reaction with 3 steps

1.1: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium carbonate / N,N-dimethyl-formamide; water / 16 h / 100 °C / Inert atmosphere

2.1: trialkylamine

2.2: 20 °C

3.1: dichloromethane / 16 h / 30 °C / Acidic conditions

With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium carbonate; In dichloromethane; water; N,N-dimethyl-formamide; 1.1: |Suzuki Coupling;
DOI:10.1016/j.bmcl.2013.09.040