4-Amino-3-fluoropyridine

Base Information

Chemical Name:4-Amino-3-fluoropyridine
CAS No.:2247-88-3
Molecular Formula:C5H5FN2
Molecular Weight:112.107
Hs Code.:29333990
European Community (EC) Number:623-648-1
UNII:Y744OES4EP
DSSTox Substance ID:DTXSID70355751
Nikkaji Number:J3.593.116C
Wikidata:Q72437416
Mol file:2247-88-3.mol

Synonyms:4-Amino-3-fluoropyridine;2247-88-3;3-fluoropyridin-4-amine;3-fluoro-4-aminopyridine;3-Fluoro-pyridin-4-ylamine;4-Pyridinamine, 3-fluoro-;MFCD00234072;Y744OES4EP;Pyridine, 4-amino-3-fluoro-;3-Amine-5-fluoropyridine;UNII-Y744OES4EP;4-amino-3-fluoro-pyridine;SCHEMBL767020;DTXSID70355751;4-Amino-3-fluoropyridine, 97%;UFIKBUVVVGSMGW-UHFFFAOYSA-N;BCP01703;CAA44788;AC-047;BBL103925;CL0178;STL557735;AKOS005063495;CS-W007902;PB33879;PS-9251;SB10494;SY008130;A4817;AM20070069;FT-0648284;FT-0751233;EN300-85350;W-201934

Suppliers and Price of 4-Amino-3-fluoropyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TCI Chemical
4-Amino-3-fluoropyridine >98.0%(GC)(T)
1g
$ 63.00

TCI Chemical
4-Amino-3-fluoropyridine >98.0%(GC)(T)
5g
$ 231.00

SynQuest Laboratories
4-Amino-3-fluoropyridine 98%
25 g
$ 675.00

SynQuest Laboratories
4-Amino-3-fluoropyridine 98%
1 g
$ 43.00

SynQuest Laboratories
4-Amino-3-fluoropyridine 98%
5 g
$ 187.00

Sigma-Aldrich
4-Amino-3-fluoropyridine 97%
1g
$ 104.00

Matrix Scientific
4-Amino-3-fluoropyridine 97%
5g
$ 49.00

Matrix Scientific
4-Amino-3-fluoropyridine 97%
25g
$ 184.00

Matrix Scientific
4-Amino-3-fluoropyridine 97%
100g
$ 642.00

Labseeker
3-FLUORO-4-AMINOPYRIDINE 98
25g
$ 554.00

Total 111 raw suppliers

Chemical Property of 4-Amino-3-fluoropyridine

Chemical Property:

Appearance/Colour:Yellow to light yellow crystals
Vapor Pressure:0.135mmHg at 25°C
Melting Point:74-77 °C
Refractive Index:1.554
Boiling Point:217.1 °C at 760 mmHg
PKA:7.19±0.12(Predicted)
Flash Point:85.1 °C
PSA：38.91000
Density:1.257 g/cm³
LogP:1.38410
Storage Temp.:Keep in dark place,Inert atmosphere,Room temperature
Solubility.:soluble in Methanol
XLogP3:0.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:112.04367633
Heavy Atom Count:8
Complexity:76.8

Purity/Quality:

99% ^*data from raw suppliers

4-Amino-3-fluoropyridine >98.0%(GC)(T) ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi; Xn
Hazard Codes:Xi,Xn
Statements: 22-36
Safety Statements: 26

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CN=CC(=C1N)F
Uses 4-Amino-3-fluoropyridine is an important intermediate in the synthesis of many new drugs, and it is an intermediate in the synthesis of transforming growth factor-β inhibitors and thrombin inhibitors.

Technology Process of 4-Amino-3-fluoropyridine

There total 7 articles about 4-Amino-3-fluoropyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 13505-01-6
3-fluoro-4-nitropyridine

: 5720-07-0
4-methoxyphenylboronic acid

: C₁₁H₉FN₂

: 2247-88-3
3-fluoro-pyridin-4-ylamine

Guidance literature:: With phenylsilane; copper diacetate; 1,4-di(diphenylphosphino)-butane; In toluene; acetonitrile; at 60 ℃; for 30h;
DOI:10.1021/acscatal.1c03113