C₁₁H₁₄ClN

Base Information

• Chemical Name: C₁₁H₁₄ClN
• CAS No.: 1448783-20-7
• Molecular Formula: C₁₁H₁₄ClN
• Molecular Weight: 195.692
• Mol file: 1448783-20-7.mol

Synonyms:C₁₁H₁₄ClN

Chemical Property of C₁₁H₁₄ClN

Chemical Property:

Purity/Quality:

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Technology Process of C₁₁H₁₄ClN

There total 1 articles about C₁₁H₁₄ClN which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-chloro-benzonitrile (766-84-7) + tert-butylmagnesium chloride (677-22-5) → C11H14ClN (1448783-20-7)

Guidance literature:

With copper(I) bromide; In diethyl ether; for 16h; Inert atmosphere; Reflux;

DOI:10.1039/c3ob40535d

Reference yield: 79.0%

C11H14ClN (1448783-20-7) + trimethylaluminum (75-24-1) → C12H16ClN

Guidance literature:

With iron(III)-acetylacetonate; 2,3-dichlorobutane; o-phenylenebis(diphenylphosphine); In tetrahydrofuran; at 70 ℃; for 12h; regioselective reaction;

DOI:10.1002/cssc.201900164

Reference yield: 77.0%

C11H14ClN (1448783-20-7) + N-(2-bromoethyl)-N-(2-propenyl)-4-methylbenzenesulfonamide (129748-56-7) → 1-(5-chloro-2-((1-tosylpyrrolidin-3-yl)methyl)phenyl)-2,2-dimethylpropan-1-imine

Guidance literature:

With 1,3-bis((S)-1-cyclohexylethyl)-4,5-dihydro-1H-imidazol-3-ium tetrafluoroborate; neopentylmagnesium bromide; cobalt(II) bromide; In tetrahydrofuran; at 20 ℃; for 12h; Schlenk technique; Cooling with ice;

DOI:10.1021/acs.orglett.9b01846

upstream raw materials:

3-chloro-benzonitrile

tert-butylmagnesium chloride

Downstream raw materials:

(S)-methyl N-(1-(3-chlorophenyl)-2,2-dimethylpropylidene)phenylalaninate