(S)-2-[(S)-2-(2-Mercapto-acetylamino)-3-phenyl-propionylamino]-3-methyl-butyric acid methyl ester

Base Information

• Chemical Name: (S)-2-[(S)-2-(2-Mercapto-acetylamino)-3-phenyl-propionylamino]-3-methyl-butyric acid methyl ester
• CAS No.: 606966-89-6
• Molecular Formula: C₁₇H₂₄N₂O₄S
• Molecular Weight: 352.455

Synonyms:(S)-2-[(S)-2-(2-Mercapto-acetylamino)-3-phenyl-propionylamino]-3-methyl-butyric acid methyl ester

Chemical Property of (S)-2-[(S)-2-(2-Mercapto-acetylamino)-3-phenyl-propionylamino]-3-methyl-butyric acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (S)-2-[(S)-2-(2-Mercapto-acetylamino)-3-phenyl-propionylamino]-3-methyl-butyric acid methyl ester

There total 2 articles about (S)-2-[(S)-2-(2-Mercapto-acetylamino)-3-phenyl-propionylamino]-3-methyl-butyric acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

(S)-2-[(S)-2-(2-Chloro-acetylamino)-3-phenyl-propionylamino]-3-methyl-butyric acid methyl ester (606966-88-5) → (S)-2-[(S)-2-(2-Mercapto-acetylamino)-3-phenyl-propionylamino]-3-methyl-butyric acid methyl ester (606966-89-6)

Guidance literature:

(S)-2-[(S)-2-(2-Chloro-acetylamino)-3-phenyl-propionylamino]-3-methyl-butyric acid methyl ester; With thiourea; In acetone; at 20 ℃;

With sodium sulfite; In water;

DOI:10.1016/S0040-4039(03)01432-1

Reference yield:

N-Z-L-phenylalanyl-L-valine methylester (4818-08-0) → (S)-2-[(S)-2-(2-Mercapto-acetylamino)-3-phenyl-propionylamino]-3-methyl-butyric acid methyl ester (606966-89-6)

Guidance literature:

Multi-step reaction with 2 steps

1.1: hydrogenolysis

1.2: 84 percent / NaHCO₃ / acetonitrile / 20 °C

2.1: thiourea / acetone / 20 °C

2.2: 61 percent / Na₂SO₃ / H₂O

With thiourea; In acetone;

DOI:10.1016/S0040-4039(03)01432-1

Reference yield: 78.0%

bis(3-chloroacetamidopropyl)-N-tert-butoxycarbonylamine (380848-84-0) + (S)-2-[(S)-2-(2-Mercapto-acetylamino)-3-phenyl-propionylamino]-3-methyl-butyric acid methyl ester (606966-89-6) → C49H73N7O12S2 (606966-92-1)

Guidance literature:

With caesium carbonate; In N,N-dimethyl-formamide; at 20 ℃;

DOI:10.1016/S0040-4039(03)01432-1

upstream raw materials:

(S)-2-[(S)-2-(2-Chloro-acetylamino)-3-phenyl-propionylamino]-3-methyl-butyric acid methyl ester

N-Z-L-phenylalanyl-L-valine methylester

Downstream raw materials:

C₄₉H₇₃N₇O₁₂S₂

C₄₆H₆₆ClN₇O₁₁S₂

C₄₆H₆₇N₇O₁₁S₃

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 606966-89-6 (S)-2-[(S)-2-(2-Mercapto-acetylamino)-3-phenyl-propionylamino]-3-methyl-butyric acid methyl ester

Send

Send

Metric Ton KG G Pound L ML

Send

Send