2-hydroxy-2-[5-(4-methylphenyl)-1,3,4-oxadiazol-2-yl]propyl 4-bromobenzoate

Base Information

Chemical Name:2-hydroxy-2-[5-(4-methylphenyl)-1,3,4-oxadiazol-2-yl]propyl 4-bromobenzoate
CAS No.:1431463-30-7
Molecular Formula:C₁₉H₁₇BrN₂O₄
Molecular Weight:417.259
Hs Code.:

Synonyms:2-hydroxy-2-[5-(4-methylphenyl)-1,3,4-oxadiazol-2-yl]propyl 4-bromobenzoate

Suppliers and Price of 2-hydroxy-2-[5-(4-methylphenyl)-1,3,4-oxadiazol-2-yl]propyl 4-bromobenzoate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-hydroxy-2-[5-(4-methylphenyl)-1,3,4-oxadiazol-2-yl]propyl 4-bromobenzoate

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Technology Process of 2-hydroxy-2-[5-(4-methylphenyl)-1,3,4-oxadiazol-2-yl]propyl 4-bromobenzoate

There total 2 articles about 2-hydroxy-2-[5-(4-methylphenyl)-1,3,4-oxadiazol-2-yl]propyl 4-bromobenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 900937-58-8
2-oxopropyl 4-bromobenzoate

: 99-94-5
p-Toluic acid

: 73789-56-7
N-isocyaniminotriphenylphosphorane

: 1431463-30-7
2-hydroxy-2-[5-(4-methylphenyl)-1,3,4-oxadiazol-2-yl]propyl 4-bromobenzoate

Guidance literature:: In water; at 20 ℃; for 1h; Green chemistry;
DOI:10.1080/10426507.2015.1054486

Reference yield:

: 2532-15-2
sodium 4-bromobenzoate

: 1431463-30-7
2-hydroxy-2-[5-(4-methylphenyl)-1,3,4-oxadiazol-2-yl]propyl 4-bromobenzoate

Guidance literature:: Multi-step reaction with 2 steps

1: N,N-dimethyl-formamide / 21 h / 100 °C

2: dichloromethane / 1 h / 20 °C

In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1002/jhet.1012