(S)-1-{4-[2-(4-Chloro-benzenesulfonyl)-4-methoxy-benzenesulfonyl]-phenyl}-ethylamine

Base Information

Chemical Name:(S)-1-{4-[2-(4-Chloro-benzenesulfonyl)-4-methoxy-benzenesulfonyl]-phenyl}-ethylamine
CAS No.:447460-30-2
Molecular Formula:C₂₁H₂₀ClNO₅S₂
Molecular Weight:465.979
Hs Code.:

Synonyms:(S)-1-{4-[2-(4-Chloro-benzenesulfonyl)-4-methoxy-benzenesulfonyl]-phenyl}-ethylamine

Suppliers and Price of (S)-1-{4-[2-(4-Chloro-benzenesulfonyl)-4-methoxy-benzenesulfonyl]-phenyl}-ethylamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (S)-1-{4-[2-(4-Chloro-benzenesulfonyl)-4-methoxy-benzenesulfonyl]-phenyl}-ethylamine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-1-{4-[2-(4-Chloro-benzenesulfonyl)-4-methoxy-benzenesulfonyl]-phenyl}-ethylamine

There total 6 articles about (S)-1-{4-[2-(4-Chloro-benzenesulfonyl)-4-methoxy-benzenesulfonyl]-phenyl}-ethylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: C₂₃H₂₂ClNO₆S₂

: 447460-30-2
(S)-1-{4-[2-(4-Chloro-benzenesulfonyl)-4-methoxy-benzenesulfonyl]-phenyl}-ethylamine

Guidance literature:: With lithium hydroxide; water; In 1,4-dioxane; at 0 - 20 ℃;

Reference yield:

: 447460-28-8
N-(1-{4-[2-(4-chloro-benzenesulfonyl)-4-methoxy-benzenesulfonyl]-phenyl}-ethyl)-2,2,2-trifluoro-acetamide

: 447460-30-2
(S)-1-{4-[2-(4-Chloro-benzenesulfonyl)-4-methoxy-benzenesulfonyl]-phenyl}-ethylamine

Guidance literature:: With lithium hydroxide; In 1,4-dioxane;
DOI:10.1016/j.bmcl.2005.07.023

Reference yield:

: 2627-86-3
(S)-1-phenyl-ethylamine

: 447460-30-2
(S)-1-{4-[2-(4-Chloro-benzenesulfonyl)-4-methoxy-benzenesulfonyl]-phenyl}-ethylamine

Guidance literature:: Multi-step reaction with 5 steps

1.1: CH₂Cl₂ / 3 h / 20 °C

2.1: 46 g / dibromodimethyl hydantoin; methanesulfonic acid / CH₂Cl₂ / 20 °C

3.1: n-BuLi / tetrahydrofuran; hexane / -78 °C

3.2: tetrahydrofuran; hexane

4.1: n-BuLi / tetrahydrofuran; hexane / -78 °C

4.2: tetrahydrofuran; hexane / -78 - 20 °C

5.1: aq. LiOH / dioxane

With lithium hydroxide; n-butyllithium; methanesulfonic acid; 1,3-dibromo-5,5-dimethylimidazolidine-2,4-dione; In tetrahydrofuran; 1,4-dioxane; hexane; dichloromethane;
DOI:10.1016/j.bmcl.2005.07.023