1-(4-(4-tetradecyloxybenzoyloxy)phenyl)-4-(4-(4-tetradecyloxybenzoyloxy)phenyl)-1H-1,2,3-triazol

Base Information

• Chemical Name: 1-(4-(4-tetradecyloxybenzoyloxy)phenyl)-4-(4-(4-tetradecyloxybenzoyloxy)phenyl)-1H-1,2,3-triazol
• CAS No.: 1394236-37-3
• Molecular Formula: C₅₆H₇₅N₃O₆
• Molecular Weight: 886.228
• Mol file: 1394236-37-3.mol

Synonyms:1-(4-(4-tetradecyloxybenzoyloxy)phenyl)-4-(4-(4-tetradecyloxybenzoyloxy)phenyl)-1H-1,2,3-triazol

Chemical Property of 1-(4-(4-tetradecyloxybenzoyloxy)phenyl)-4-(4-(4-tetradecyloxybenzoyloxy)phenyl)-1H-1,2,3-triazol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(4-(4-tetradecyloxybenzoyloxy)phenyl)-4-(4-(4-tetradecyloxybenzoyloxy)phenyl)-1H-1,2,3-triazol

There total 5 articles about 1-(4-(4-tetradecyloxybenzoyloxy)phenyl)-4-(4-(4-tetradecyloxybenzoyloxy)phenyl)-1H-1,2,3-triazol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

4-azidophenyl 4-tetradecyloxybenzoate (1394236-23-7) + 4-ethynylphenyl 4-tetradecyloxybenzoate (142663-61-4) → 1-(4-(4-tetradecyloxybenzoyloxy)phenyl)-4-(4-(4-tetradecyloxybenzoyloxy)phenyl)-1H-1,2,3-triazol (1394236-37-3)

Guidance literature:

With C₃₀H₂₇ClCuN₉O; In tetrahydrofuran; N,N-dimethyl-formamide; at 80 ℃; for 1h; Microwave irradiation;

DOI:10.1039/c2jm33612j

Reference yield:

4-hydroxy-benzaldehyde (123-08-0,65581-83-1) → 1-(4-(4-tetradecyloxybenzoyloxy)phenyl)-4-(4-(4-tetradecyloxybenzoyloxy)phenyl)-1H-1,2,3-triazol (1394236-37-3)

Guidance literature:

Multi-step reaction with 4 steps

1.1: triphenylphosphine / dichloromethane / 1 h / 0 °C

1.2: 2 h / 0 °C

2.1: n-butyllithium / tetrahydrofuran; hexane / 1 h / -78 °C

2.2: 0.5 h / -78 °C

3.1: dmap; dicyclohexyl-carbodiimide / dichloromethane / 16 h / 20 °C / Inert atmosphere; Cooling with ice

4.1: C₃₀H₂₇ClCuN₉O / N,N-dimethyl-formamide; tetrahydrofuran / 1 h / 80 °C / Microwave irradiation

With dmap; n-butyllithium; C₃₀H₂₇ClCuN₉O; dicyclohexyl-carbodiimide; triphenylphosphine; In tetrahydrofuran; hexane; dichloromethane; N,N-dimethyl-formamide;

DOI:10.1039/c2jm33612j

Reference yield:

4-ethynylphenol (2200-91-1) → 1-(4-(4-tetradecyloxybenzoyloxy)phenyl)-4-(4-(4-tetradecyloxybenzoyloxy)phenyl)-1H-1,2,3-triazol (1394236-37-3)

Guidance literature:

Multi-step reaction with 2 steps

1: dmap; dicyclohexyl-carbodiimide / dichloromethane / 16 h / 20 °C / Inert atmosphere; Cooling with ice

2: C₃₀H₂₇ClCuN₉O / N,N-dimethyl-formamide; tetrahydrofuran / 1 h / 80 °C / Microwave irradiation

With dmap; C₃₀H₂₇ClCuN₉O; dicyclohexyl-carbodiimide; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;

DOI:10.1039/c2jm33612j

upstream raw materials:

4-azidophenyl 4-tetradecyloxybenzoate

4-ethynylphenyl 4-tetradecyloxybenzoate

4-amino-phenol

4-hydroxy-benzaldehyde

Refernces