1-(2,4-Dinitro-phenyl)-2-[1,3,3-trimethyl-1,3-dihydro-indol-(2E)-ylidene]-ethanone

Base Information

• Chemical Name: 1-(2,4-Dinitro-phenyl)-2-[1,3,3-trimethyl-1,3-dihydro-indol-(2E)-ylidene]-ethanone
• CAS No.: 113639-17-1
• Molecular Formula: C₁₉H₁₇N₃O₅
• Molecular Weight: 367.361
• Mol file: 113639-17-1.mol

Synonyms:1-(2,4-Dinitro-phenyl)-2-[1,3,3-trimethyl-1,3-dihydro-indol-(2E)-ylidene]-ethanone

Chemical Property of 1-(2,4-Dinitro-phenyl)-2-[1,3,3-trimethyl-1,3-dihydro-indol-(2E)-ylidene]-ethanone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-(2,4-Dinitro-phenyl)-2-[1,3,3-trimethyl-1,3-dihydro-indol-(2E)-ylidene]-ethanone

There total 2 articles about 1-(2,4-Dinitro-phenyl)-2-[1,3,3-trimethyl-1,3-dihydro-indol-(2E)-ylidene]-ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

2,4-dinitrobenzoyl chloride (20195-22-6) + 1,3,3-Trimethyl-2-methyleneindoline (118-12-7) → 1-(2,4-Dinitro-phenyl)-2-[1,3,3-trimethyl-1,3-dihydro-indol-(2E)-ylidene]-ethanone (113639-17-1)

Guidance literature:

With triethylamine; In benzene; at 40 ℃; for 2h; 20 degC, overnight;

DOI:10.1007/BF00475641

Reference yield:

2,4-dinitrobenzoic acid (610-30-0) → 1-(2,4-Dinitro-phenyl)-2-[1,3,3-trimethyl-1,3-dihydro-indol-(2E)-ylidene]-ethanone (113639-17-1)

Guidance literature:

Multi-step reaction with 2 steps

1: SOCl₂ / benzene / 1.5 h / Heating

2: 65 percent / triethylamine / benzene / 2 h / 40 °C / 20 degC, overnight

With thionyl chloride; triethylamine; In benzene;

DOI:10.1007/BF00475641

Reference yield: 39.0%

1-(2,4-Dinitro-phenyl)-2-[1,3,3-trimethyl-1,3-dihydro-indol-(2E)-ylidene]-ethanone (113639-17-1) → 1,3,3-trimethyl-1,3-dihydro-2H-indol-2-one (20200-86-6) + 1-ethynyl-2,4-dinitrobenzene (18436-61-8)

Guidance literature:

With trichlorophosphate; In 1,4-dioxane; at 80 ℃; for 4h; Yields of byproduct given;

DOI:10.1007/BF00475641

upstream raw materials:

2,4-dinitrobenzoyl chloride

1,3,3-Trimethyl-2-methyleneindoline

2,4-dinitrobenzoic acid

Downstream raw materials:

1,3,3-trimethyl-1,3-dihydro-2H-indol-2-one

1-ethynyl-2,4-dinitrobenzene