(2-(4-(3-azidopropoxy)phenyl)ethene-1,1,2-triyl)tribenzene

Base Information

• Chemical Name: (2-(4-(3-azidopropoxy)phenyl)ethene-1,1,2-triyl)tribenzene
• CAS No.: 1535166-44-9
• Molecular Formula: C₂₉H₂₅N₃O
• Molecular Weight: 431.537
• Mol file: 1535166-44-9.mol

Synonyms:(2-(4-(3-azidopropoxy)phenyl)ethene-1,1,2-triyl)tribenzene

Chemical Property of (2-(4-(3-azidopropoxy)phenyl)ethene-1,1,2-triyl)tribenzene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2-(4-(3-azidopropoxy)phenyl)ethene-1,1,2-triyl)tribenzene

There total 4 articles about (2-(4-(3-azidopropoxy)phenyl)ethene-1,1,2-triyl)tribenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.1%

(2-(4-(3-bromopropoxy)phenyl)ethene-1,1,2-triyl)tribenzene → (2-(4-(3-azidopropoxy)phenyl)ethene-1,1,2-triyl)tribenzene (1535166-44-9)

Guidance literature:

With sodium azide; In N,N-dimethyl-formamide; at 80 ℃; for 2h; Microwave irradiation;

DOI:10.1016/j.tet.2021.132509

Reference yield: 82.1%

1-(4'-hydroxyphenyl)-1,2,2-triphenylethylene (76115-06-5) + toluenesulfonic acid 3-azidopropyl ester (153207-76-2) → (2-(4-(3-azidopropoxy)phenyl)ethene-1,1,2-triyl)tribenzene (1535166-44-9)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 80 ℃;

DOI:10.1002/chem.201303679

Reference yield:

4-Hydroxybenzophenone (1137-42-4) → (2-(4-(3-azidopropoxy)phenyl)ethene-1,1,2-triyl)tribenzene (1535166-44-9)

Guidance literature:

Multi-step reaction with 3 steps

1.1: pyridine; titanium tetrachloride; zinc / tetrahydrofuran / Reflux

2.1: potassium carbonate / acetonitrile / 0.5 h / Reflux

2.2: 12 h / Inert atmosphere; Reflux

3.1: sodium azide / N,N-dimethyl-formamide / 2 h / 80 °C / Microwave irradiation

With pyridine; sodium azide; titanium tetrachloride; potassium carbonate; zinc; In tetrahydrofuran; N,N-dimethyl-formamide; acetonitrile; 1.1: |McMurry Reaction;

DOI:10.1016/j.tet.2021.132509

upstream raw materials:

1-(4'-hydroxyphenyl)-1,2,2-triphenylethylene

toluenesulfonic acid 3-azidopropyl ester

4-Hydroxybenzophenone

benzophenone