C₂₅H₂₅BrFNO

Base Information

• Chemical Name: C₂₅H₂₅BrFNO
• CAS No.: 1373125-72-4
• Molecular Formula: C₂₅H₂₅BrFNO
• Molecular Weight: 454.382
• Mol file: 1373125-72-4.mol

Synonyms:C₂₅H₂₅BrFNO

Chemical Property of C₂₅H₂₅BrFNO

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₅H₂₅BrFNO

There total 4 articles about C₂₅H₂₅BrFNO which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C17H17BrFN + p-Methoxybenzyl bromide (2746-25-0) → C25H25BrFNO (1373125-72-4)

Guidance literature:

C₁₇H₁₇BrFN; With sodium hexamethyldisilazane; In tetrahydrofuran; at 0 ℃; for 1h;

p-Methoxybenzyl bromide; In tetrahydrofuran; at 0 - 20 ℃;

DOI:10.1016/j.tetlet.2012.02.096

Reference yield:

C13H9BrFN (405284-40-4) → C25H25BrFNO (1373125-72-4)

Guidance literature:

Multi-step reaction with 2 steps

1.1: magnesium sulfate / tetrahydrofuran / 0 °C

2.1: sodium hexamethyldisilazane / tetrahydrofuran / 1 h / 0 °C

2.2: 0 - 20 °C

With sodium hexamethyldisilazane; magnesium sulfate; In tetrahydrofuran;

DOI:10.1016/j.tetlet.2012.02.096

Reference yield:

4-fluorobenzaldehyde (459-57-4) → C25H25BrFNO (1373125-72-4)

Guidance literature:

Multi-step reaction with 3 steps

1.1: magnesium sulfate / dichloroethane / 65 °C

2.1: magnesium sulfate / tetrahydrofuran / 0 °C

3.1: sodium hexamethyldisilazane / tetrahydrofuran / 1 h / 0 °C

3.2: 0 - 20 °C

With sodium hexamethyldisilazane; magnesium sulfate; In tetrahydrofuran; dichloroethane;

DOI:10.1016/j.tetlet.2012.02.096

upstream raw materials:

C₁₃H₉BrFN

p-Methoxybenzyl bromide

4-fluorobenzaldehyde

2-bromoaniline

Refernces