Chloroacetyl-dl-norleucine

Base Information

• Chemical Name: Chloroacetyl-dl-norleucine
• CAS No.: 67206-26-2
• Molecular Formula: C8H14ClNO3
• Molecular Weight: 207.65
• Hs Code.: 2924199090
• European Community (EC) Number: 679-586-0
• NSC Number: 203446,270562
• Mol file: 67206-26-2.mol

Synonyms:Chloroacetyl-dl-norleucine;67206-26-2;N-Chloroacetyl-DL-norleucine;2-[(2-chloroacetyl)amino]hexanoic acid;2-(2-chloroacetamido)hexanoic acid;N-(Chloroacetyl)-DL-norleucine;NSC203446;Chloracetyl-d,l-norleucin;N-(Chloroacetyl)norleucine;N-(Chloroacetyl)norleucine #;SCHEMBL11736289;NTOGPWIZAGBRID-UHFFFAOYSA-N;MFCD00059650;NSC270562;HY-W142018;NSC-203446;NSC-270562;CS-0201804;FT-0702411;T71203

Chemical Property of Chloroacetyl-dl-norleucine

Chemical Property:

• Vapor Pressure: 7.44E-08mmHg at 25°C
• Melting Point: 113 °C
• Refractive Index: 1.479
• Boiling Point: 409.6 °C at 760 mmHg
• Flash Point: 201.5 °C
• PSA: 66.40000
• Density: 1.2 g/cm³
• LogP: 1.37570
• Solubility.: almost transparency in Methanol
• XLogP3: 1.6
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 6
• Exact Mass: 207.0662210
• Heavy Atom Count: 13
• Complexity: 184

Purity/Quality:

98%,99%, ^*data from raw suppliers

N-Chloroacetyl-DL-norleucine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCC(C(=O)O)NC(=O)CCl

Technology Process of Chloroacetyl-dl-norleucine

There total 4 articles about Chloroacetyl-dl-norleucine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-amino-hexanoic acid (616-06-8) + chloroacetyl chloride (79-04-9) → 2-(2-chloroacetamido)hexanoic acid (67206-26-2)

Guidance literature:

With alkali;

Reference yield:

2-bromohexanoic acid (616-05-7) → 2-(2-chloroacetamido)hexanoic acid (67206-26-2)

Guidance literature:

Multi-step reaction with 2 steps

1: ammonia / 37 °C

2: alkali

With ammonia;

Reference yield:

hexanoic acid (142-62-1) → 2-(2-chloroacetamido)hexanoic acid (67206-26-2)

Guidance literature:

Multi-step reaction with 3 steps

1: phosphorus trichloride; bromine / 65 - 100 °C

2: ammonia / 37 °C

3: alkali

With ammonia; bromine; phosphorus trichloride;

upstream raw materials:

2-amino-hexanoic acid

chloroacetyl chloride

2-bromohexanoic acid

hexanoic acid